Evidence map›Paper›PMID 28707963›Full record

ArticleRadiology2017

In Vivo Assessment of Ovarian Tumor Response to Tyrosine Kinase Inhibitor Pazopanib by Using Hyperpolarized

Murali K Ravoori, Sheela P Singh, Jaehyuk Lee, James A Bankson, Vikas Kundra

Registry-linked trialAbstract readEvaluation Study
In one paragraph

Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697406 (Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05697406 phase1 / phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2024 to 2028Enrolled25ConditionsImage, Warburg Effect, TumorsArmsHyperpolarized 13C-Pyruvate
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. A Simulation of the Effects of Diffusion on Hyperpolarized [1-IEEE transactions on bio-medical engineering · 2023
    Article
  5. Review
  6. Article
  7. Hyperpolarized Carbon-13 MRI in Breast Cancer.Diagnostics (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Review
  10. Hyperpolarized [1-Molecular imaging and biology · 2022
    Article
  11. Article
  12. Offset of apparent hyperpolarizedNMR in biomedicine · 2021
    Article
  13. Article
  14. The use of hyperpolarisedBritish journal of cancer · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Assessment ofScientific reports · 2019
    Article
  19. HyperpolarizedRadiology · 2019
    Review
  20. Targeting tumor-associated acidity in cancer immunotherapy.Cancer immunology, immunotherapy : CII · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Murali K RavooriFrom the Departments of Cancer Systems Imaging (M.K.R., S.P.S., V.K.), Imaging Physics (J.L., J.A.B.), and Diagnostic Radiology (V.K.), University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
Sheela P SinghFrom the Departments of Cancer Systems Imaging (M.K.R., S.P.S., V.K.), Imaging Physics (J.L., J.A.B.), and Diagnostic Radiology (V.K.), University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
Jaehyuk LeeFrom the Departments of Cancer Systems Imaging (M.K.R., S.P.S., V.K.), Imaging Physics (J.L., J.A.B.), and Diagnostic Radiology (V.K.), University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
James A BanksonFrom the Departments of Cancer Systems Imaging (M.K.R., S.P.S., V.K.), Imaging Physics (J.L., J.A.B.), and Diagnostic Radiology (V.K.), University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
Vikas KundraFrom the Departments of Cancer Systems Imaging (M.K.R., S.P.S., V.K.), Imaging Physics (J.L., J.A.B.), and Diagnostic Radiology (V.K.), University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Personalizing Nanoparticle TherapyR01CA159042 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KUNDRA, VIKAS · 2011 to 2015
$1.6M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA159042
6 · The paper itself

Abstract

Purpose To assess in a mouse model whether early or late components of glucose metabolism, exemplified by fluorine 18 (

Indexed as

AnimalsAntineoplastic AgentsCarbon-13 Magnetic Resonance SpectroscopyCell Line, TumorDrug MonitoringFemaleFluorodeoxyglucose F18HumansIndazolesMagnetic Resonance ImagingMiceMice, NudeMolecular ImagingMultimodal ImagingOutcome Assessment, Health CareOvarian NeoplasmsAntineoplastic AgentsFluorodeoxyglucose F18IndazolespazopanibProtein-Tyrosine KinasesPyrimidinesRadiopharmaceuticalsSulfonamides

Identifiers

PMID28707963
PMCPMC5708291
OpenAlexW2734646747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.