Evidence map›Paper›PMID 28707960›Full record

ArticleRadiology2017

Biofunctionalized Hybrid Magnetic Gold Nanoparticles as Catalysts for Photothermal Ablation of Colorectal Liver Metastases.

Sarah B White, Dong-Hyun Kim, Yang Guo, Weiguo Li, Yihe Yang, Jeane Chen, Venkateswara R Gogineni, Andrew C Larson

Abstract read
In one paragraph

Article in Radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Transarterial Embolization of Liver Cancer in a Transgenic Pig Model.Journal of vascular and interventional radiology : JVIR · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Photothermal therapy technology of metastatic colorectal cancer.American journal of translational research · 2020
    Review
  13. Article
  14. Review
  15. Article
  16. Image-Guided Cancer Nanomedicine.Journal of imaging · 2018
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sarah B WhiteFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Dong-Hyun KimFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Yang GuoFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Weiguo LiFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Yihe YangFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Jeane ChenFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Venkateswara R GogineniFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Andrew C LarsonFrom the Department of Radiology, Division of Vascular and Interventional Radiology, Medical College of Wisconsin, Milwaukee, Wis (S.B.W., V.R.G.); Department of Radiology (S.B.W., D.H.K., Y.G., W.L., Y.Y., J.C., A.C.L.) and Robert H. Lurie Comprehensive Cancer Center (D.H.K., A.C.L.), Northwestern University, 710 N Fairbanks Ct, Olson 8th floor 8-317, Chicago, IL 60611; Department of Chemical and Biological Engineering (J.C.) and Department of Biomedical Engineering (A.C.L.), Northwestern University, Evanston, Ill.
Northwestern University · USMedical College of Wisconsin · US

Funding

Cancer Nanotechnology in Imaging and RadiotherapyR25CA132822 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLOSCHAK, GAYLE E. · 2009 to 2013
$2.0M
NCI NIH HHS R25 CA132822
6 · The paper itself

Abstract

Purpose To demonstrate that anti-MG1 conjugated hybrid magnetic gold nanoparticles (HNPs) act as a catalyst during photothermal ablation (PTA) of colorectal liver metastases, and thus increase ablation zones. Materials and Methods All experiments were performed with approval of the institutional animal care and use committee. Therapeutic and diagnostic multifunctional HNPs conjugated with anti-MG1 monoclonal antibodies were synthesized, and the coupling efficiency was determined. Livers of 19 Wistar rats were implanted with 5 × 10

Indexed as

AnimalsAntibodies, MonoclonalCell Line, TumorColorectal NeoplasmsGoldHyperthermia, InducedLiver NeoplasmsLow-Level Light TherapyMagnetite NanoparticlesMucin-5BNanoconjugatesRatsRats, WistarTreatment OutcomeAntibodies, MonoclonalGoldMagnetite NanoparticlesMUC5B protein, humanMucin-5BNanoconjugates

Identifiers

PMID28707960
PMCPMC5708290
OpenAlexW2735786966

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.