SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017
Thymectomy is a beneficial therapy for patients with non-thymomatous ocular myasthenia gravis: a systematic review and meta-analysis.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 59 citations in OpenAlex.
- Thymectomy with or without maintenance therapy for myasthenia gravis patients: a tri-center, real-world study.Therapeutic advances in neurological disorders · 2026Article
- Thymectomy in Ocular Myasthenia Gravis: Results Before and After Generalization and Prognostic Predictors of Outcomes.Journal of clinical medicine · 2025Article
- Clinical study of thyroid eye disease combined with myasthenia gravis.Japanese journal of ophthalmology · 2025Article
- Robotic Thymectomy for Myasthenia Gravis: Analysis of the Surgical and Neurological Outcomes After a 20 Years' Experience.European journal of neurology · 2025Article
- Robotic thymectomy for ocular myasthenia gravis: a case series from a UK tertiary centre.BMJ neurology open · 2025Article
- Application of efgartigimod in Chinese patients with myasthenia gravis: a single-center real-world prospective study.Therapeutic advances in neurological disorders · 2025Article
- Physiological and pathological roles of the thymus and value of thymectomy in myasthenia gravis: a narrative review.Mediastinum (Hong Kong, China) · 2024Review
- Myasthenia Gravis: Novel Findings and Perspectives on Traditional to Regenerative Therapeutic Interventions.Aging and disease · 2023Article
- Insights from a Case of Good's Syndrome (Immunodeficiency with Thymoma).Biomedicines · 2023Article
- Predictive factors for postoperative myasthenic crisis in patients with myasthenia gravis.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- The Role of Thymoma and Thymic Hyperplasia as Prognostic Risk Factors for Secondary Generalisation in Adults with Ocular Myasthenia Gravis: A Systematic Narrative Review.The British and Irish orthoptic journal · 2023Article
- Guideline for the management of myasthenic syndromes.Therapeutic advances in neurological disorders · 2023Review
- Ocular Myasthenia Gravis: A Current Overview.Eye and brain · 2023Review
- Thymectomy in ocular myasthenia gravis-prognosis and risk factors analysis.Orphanet journal of rare diseases · 2022Article
- Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome: New Developments in Diagnosis and Treatment.Neuropsychiatric disease and treatment · 2022Review
- [The value of thymectomy in the treatment of non-thymomatous myasthenia gravis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Review
- Thymectomy and Risk of Generalization in Patients with Ocular Myasthenia Gravis: A Multicenter Retrospective Cohort Study.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021Article
- Review
- Outcomes After Transcervical Thymectomy for Ocular Myasthenia Gravis: A Retrospective Cohort Study With Inverse Probability Weighting.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2020Article
- Prognostic predictors of remission in ocular myasthenia after thymectomy.Journal of thoracic disease · 2020Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Ocular myasthenia gravis, an autoimmune disease, is characterized by extraocular muscle weakness. Myasthenia gravis is closely associated with the functional status of the thymus gland. The efficacy of thymectomy for non-thymomatous ocular myasthenia gravis remains controversial. Here, we present the first systematic review and meta-analysis of studies assessing the outcome of thymectomy in patients with non-thymomatous ocular myasthenia gravis and found that the pooled rate of complete stable remission was 0.5074 with considerable heterogeneity. Furthermore, subgroup analysis showed that the efficacy of thymectomy differed according to geographical location. Furthermore, thymectomy outcomes are better in children than they are in adults. Thymectomy clearly represents an effective treatment for patients with non-thymomatous ocular myasthenia gravis. However, more multicenter, randomized, controlled clinical trials are now required to confirm these conclusions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.