Evidence map›Paper›PMID 28707001›Full record

ArticleHeliyon2017

Abdominal symptoms in general practice: Frequency, cancer suspicions raised, and actions taken by GPs in six European countries. Cohort study with prospective registration of cancer.

Knut Holtedahl, Peter Vedsted, Lars Borgquist, Gé A Donker, Frank Buntinx, David Weller, Tonje Braaten, Peter Hjertholm, Jörgen Månsson, Eva Lena Strandberg and 3 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Understanding the role of GPs' gut feelings in diagnosing cancer in primary care: a systematic review and meta-analysis of existing evidence.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Pooled it
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  15. Challenges in early diagnosis of cancer: the fast track.Scandinavian journal of primary health care · 2020
    Article
  16. Observational
  17. Abdominal symptoms and cancer in the abdomen: prospective cohort study in European primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
  18. Possible missed opportunities for diagnosing colorectal cancer in Dutch primary care: a multimethods approach.The British journal of general practice : the journal of the Royal College of General Practitioners · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 6 countries.

Knut HoltedahlDepartment of Community Medicine, UiT The Arctic University of Norway, Norway.
Peter VedstedAarhus University, Research Unit for General Practice, Research Centre for Cancer Diagnosis in Primary Care, Denmark.
Lars BorgquistLinköping University, Department of Medical and Health Sciences, Sweden.
Gé A DonkerNIVEL Primary Care Database, Sentinel Practices, P.O. Box 1568, 3500 BN, Utrecht, Netherlands.
Frank BuntinxDept of General Practice, KULeuven, Belgium, and Maastricht University, Netherlands.
David WellerUsher Institute for Population Health Sciences and Medical Informatics, The University of Edinburgh, Doorway 1, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK.
Tonje BraatenDepartment of Community Medicine, UiT The Arctic University of Norway, Norway.
Peter HjertholmAarhus University, Research Unit for General Practice, Research Centre for Cancer Diagnosis in Primary Care, Denmark.
Jörgen MånssonDepartment of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at the University of Gothenburg, Sweden.
Eva Lena StrandbergLund University, Department of Clinical Sciences Malmö, Family Medicine/General Practice, Sweden.
Christine CampbellUsher Institute for Population Health Sciences and Medical Informatics, The University of Edinburgh, Doorway 1, Teviot Place, Edinburgh, EH8 9AG, Scotland, UK.
Lisbeth EllegaardDepartment of Community Medicine, UiT The Arctic University of Norway, Norway.
Ranjan ParajuliDepartment of Community Medicine, UiT The Arctic University of Norway, Norway.
UiT The Arctic University of Norway · NOAarhus University · DKUniversity of Edinburgh · GBKU Leuven · BELinköping University · SELund University · SENetherlands Institute for Health Services Research · NLUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbdominal symptoms are diagnostically challenging to general practitioners (GPs): although common, they may indicate cancer. In a prospective cohort of patients, we examined abdominal symptom frequency, initial diagnostic suspicion, and actions of GPs in response to abdominal symptoms.

methodsOver a 10-day period, 493 GPs in Norway, Denmark, Sweden, Belgium, the Netherlands, and Scotland, recorded consecutive consultations: sex, date of birth and any specified abdominal symptoms. For patients with abdominal symptoms, additional data on non-specific symptoms, GPs' diagnostic suspicion, and features of the consultation were noted. Data on all cancer diagnoses among all included patients were requested from the GPs eight months later.

findingsConsultations with 61802 patients were recorded. Abdominal symptoms were recorded in 6264 (10.1%) patients. A subsequent malignancy was reported in 511 patients (0.8%): 441 (86.3%) had a new cancer, 70 (13.7%) a recurrent cancer. Abdominal symptoms were noted in 129 (25.2%) of cancer patients (

interpretationAbdominal symptoms pointed to abdominal cancers rather than to other cancers. However, the finding of abdominal symptoms in only one third of patients with an abdominal cancer, and the lack of cancer suspicion in a quarter of symptomatic cancer patients, provide challenges for GPs' diagnostic thinking and referral practices.

Indexed as

Evidence-based medicineMedicineOncologyPublic health

Identifiers

PMID28707001
PMCPMC5484975
OpenAlexW2650715939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.