ArticleScience advances2017
Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades.
Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 103 citations in OpenAlex.
- Comparative analysis of naked mole-rat thermogenesis and its potential to maintain euthermia in response to cold.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Body Temperature Regulation in the Rat by Muscle Tone.Acta physiologica (Oxford, England) · 2026Article
- Transcriptomic insights into the immune responses of the lung and muscle of non-healthy harbor porpoises (Frontiers in immunology · 2026Article
- Cetacean loss of the master adipose tissue regulator βNature communications · 2025Article
- Natural Mutation in Naked Mole-Rat UCP1 Refutes Importance of the Histidine Pair Motif for Proton Conductance and Thermogenesis.Acta physiologica (Oxford, England) · 2025Article
- The mitochondrial uncoupling proteins in early-branching animals: comparative analysis and transcriptional response to temperature in the jellyfish Stomolophus sp.2.Journal of bioenergetics and biomembranes · 2025Article
- Article
- Identification of a molecular resistor that controls UCP1-independent CaCell metabolism · 2025Article
- Evolution ofInternational journal of molecular sciences · 2025Article
- Emerging debates and resolutions in brown adipose tissue research.Cell metabolism · 2025Review
- Molecular evolution of TRPC4 regulatory sequences supports a role in mammalian thermoregulatory adaptation.PeerJ · 2025Article
- Potential Role of Pig UCP3 in Modulating Adipocyte Browning via the Beta-Adrenergic Receptor Signaling Pathway.Biology · 2024Article
- The Role ofCells · 2024Article
- Terrestrial Birth and Body Size Tune UCP1 Functionality in Seals.Molecular biology and evolution · 2024Article
- Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle.iScience · 2024Article
- Thermal Adaptations in Animals: Genes, Development, and Evolution.Advances in experimental medicine and biology · 2024Review
- Thermoregulation in the wild boar (Sus scrofa).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023Article
- Review
- Dynamic chromatin architecture of the porcine adipose tissues with weight gain and loss.Nature communications · 2023Article
- Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondrial uncoupling protein 1 (UCP1) is essential for nonshivering thermogenesis in brown adipose tissue and is widely accepted to have played a key thermoregulatory role in small-bodied and neonatal placental mammals that enabled the exploitation of cold environments. We map
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.