Evidence map›Paper›PMID 28706943›Full record

ArticleBioMed research international2017

Correlation of IOP with Corneal Acoustic Impedance in Porcine Eye Model.

Jun Zhang, Yi Zhang, Yang Li, Ruimin Chen, K Kirk Shung, Grace Richter, Qifa Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun ZhangCollege of Power and Mechanical Engineering, Wuhan University, Hubei, Wuhan 430072, China.ORCID 0000-0002-5213-0857
Yi ZhangUSC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Yang LiDepartment of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.
Ruimin ChenDepartment of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.
K Kirk ShungDepartment of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.
Grace RichterUSC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Qifa ZhouDepartment of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.

Funding

High Resolution Elastograpy of Retina Under Prosthetic Electrical StimulationR01EY026091 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, ZHOU, QIFA · 2016 to 2019
$2.0M
NEI NIH HHS R01 EY026091
6 · The paper itself

Abstract

purposeThe aim of this study is to correlate the intraocular pressure (IOP) change with the acoustic impedance of the cornea, in order to propose a noncontact and noninvasive method for IOP monitoring. METHODS AND MATERIALS: A highly focused transducer (frequency 47-MHz; bandwidth 62%) was made to measure the echo from the anterior and posterior surfaces of intact porcine eyes, respectively. A multilayered transmission and reflection model was used to calculate the acoustic impedance. The linear relationship between acoustic impedance and intraocular pressure was analyzed by statistical method.

resultDuring pressure elevation from 10 mm Hg to 50 mm Hg, the mean acoustic impedance of the posterior cornea increased from 1.5393 to 1.5698 MRayl, which showed a strong linear correlation (

conclusionThis study revealed a linear correlation between intraocular pressure and acoustic impedance of the cornea, thus demonstrating a potentially important method to noninvasively measure the intraocular pressure in vivo.

Indexed as

Intraocular PressureAcoustic Impedance TestsAnimalsCorneaElectric ImpedanceHumansSwineTonometry, Ocular

Identifiers

PMID28706943
PMCPMC5494779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.