Evidence map›Paper›PMID 28706785›Full record

ArticleJournal of oral biology and craniofacial research

Effect of in-situ application of simvastatin gel in surgical management of osseous defects in chronic periodontitis-A randomized clinical trial.

Rajeev Ranjan, Sudhir R Patil, Veena H R

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rajeev RanjanDepartment of Periodontics and Oral Implantology, Kalinga Institute of Dental Sciences, Campus 5, KIIT University, Patia, Bhubaneswar, Odisha, 751024, India.
Sudhir R PatilDepartment of Periodontics, K.L.E Society's Institute of Dental Sciences, Number 20, Tumkur Road, Yeshavanthpur Suburbs, suburb Bangalore, 560022, India.
Veena H RDepartment of Periodontics, K.L.E Society's Institute of Dental Sciences, Number 20, Tumkur Road, Yeshavanthpur Suburbs, suburb Bangalore, 560022, India.
Kamineni Institute of Dental Sciences · INKIIT University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present randomized controlled clinical study was designed to investigate the effect of in situ application of 1.2 mg Simvastatin (SV) gel in the surgical management of Intrabony defects in chronic periodontitis patients. METHODOLOGY: 20 patients contributing 40 sites were categorized into two treatment groups: Open flap debridement plus 1.2 mg SV gel (Group 1) and Open flap debridement plus Placebo gel (Group 2). Gingival index (GI), Plaque index (PI), Pocket depth (PD) and clinical attachment level (CAL) were recorded at baseline, 3 months, 6 months and 9 months. At baseline and at the end of 6 and 9 months Radiographic evaluation of Intrabony defect fill was done using Image j software.

resultsSignificant reduction of GI, PD and gain in CAL was observed at the end of 9 months in both groups. Amount of bone fill and percentage of original defect fill in Group 1 was statistically highly significant than Group 2 at the end of 6 and 9 months.

conclusionHigher amount of decrease in GI and PD along with more amount of CAL gain was observed in treatment group than control group. Radiological assessment confirmed that significant intrabony defect fill and percentage fill of original defect in treatment group than controlled group.

Indexed as

Chronic Periodontitisdefect fillosseous defectsSimvastatin

Identifiers

PMID28706785
PMCPMC5497385
OpenAlexW2620339684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.