Evidence map›Paper›PMID 28706608›Full record

ArticleAvicenna journal of medical biotechnology

The Effects of

Niloofar Bazazzadegan, Marzieh Dehghan Shasaltaneh, Kioomars Saliminejad, Koorosh Kamali, Mehdi Banan, Hamid Reza Khorram Khorshid

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Sweet Clover (Molecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Identification and Investigation of miRNAs FromFrontiers in pharmacology · 2020
    Article
  4. The Effect of Electroacupuncture versus Manual Acupuncture through the Expression of TrkB/NF-Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Niloofar BazazzadeganGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Marzieh Dehghan ShasaltanehLaboratory of Neuro-organic Chemistry, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran.
Kioomars SaliminejadReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Koorosh KamaliReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Mehdi BananGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Hamid Reza Khorram KhorshidGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
University of Social Welfare and Rehabilitation Sciences · IRAcademic Center for Education, Culture and Research · IRBiotechnology Research Center · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPossible mechanisms of Alzheimer Disease (AD) such as inflammation and oxidative stresses in the brain led us to investigate potential AD therapeutics of

methodsThese genes were chosen to be investigated for neuroprotective effects of the extract by comparing the expression level in the hippocampus of Sporadic AD (SAD) rat model using quantitative polymerase chain reaction (qPCR) in the treated and untreated groups. In addition, therapeutic effects at the behavioral, learning and memory level by Morris Water Maze (MWM) test were investigated.

resultsThe results represented significant decreased expression in

conclusionIt seems that the herbal extract may have significant effect on Alzheimer-related gene expression changes but not on clinical levels.

Indexed as

Alzheimer diseaseGene expressionHerbal medicine

Identifiers

PMID28706608
PMCPMC5501140
OpenAlexW2737513031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.