Evidence map›Paper›PMID 28706583›Full record

ReviewWorld journal of cardiology2017

Cardiac damage in athlete's heart: When the "supernormal" heart fails!

Andreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Maurizio Galderisi, Eduardo Bossone and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in World journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Guideline
  2. Modifiable Risk Factors in Atrial Fibrillation: Clinical Implications and Pathophysiological Insights.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Review
  3. Article
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  7. Diastolic function and dysfunction in athletes.European heart journal. Cardiovascular Imaging · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Andreina CarboneAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Antonello D'AndreaAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Lucia RieglerAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Raffaella ScarafileAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Enrica PezzulloAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Francesca MartoneAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Raffaella AmericaAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Biagio LiccardoAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Maurizio GalderisiAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Eduardo BossoneAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Raffaele CalabròAndreina Carbone, Antonello D'Andrea, Lucia Riegler, Raffaella Scarafile, Enrica Pezzullo, Francesca Martone, Raffaella America, Biagio Liccardo, Raffaele Calabrò, Chair of Cardiology, Second University of Naples, Monaldi Hospital, AORN Ospedali dei Colli, 80131 Naples, Italy.
Nuovo Ospedale San Giovanni di Dio · ITUniversity of Campania "Luigi Vanvitelli" · ITFederico II University Hospital · ITOspedale Monaldi · ITCreative Research Enterprises (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded.

Indexed as

Anabolic-androgenic steroidsArrhythmogenic dysplasia of the right ventricleAthlete’s heartAtrial fibrillationCardiac damageDopingFibrosisHypertrophic cardiomyopathyIntense exercise

Identifiers

PMID28706583
PMCPMC5491465
OpenAlexW2704211856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.