ReviewFrontiers in neurology2017
Hypertrophic Olivary Degeneration and Palatal or Oculopalatal Tremor.
Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
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Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- Hemi-see-saw nystagmus with superimposed pendular oculopalatal tremor: case report and systematic review.Journal of neurology · 2026Pooled it
- Hypertrophic Olivary Degeneration Following Brainstem Hemorrhage in a Patient with Tremor: A Case Report with Serial MRI Follow-Up.Journal of clinical medicine · 2026Article
- The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis.Movement disorders clinical practice · 2026Review
- Mutation in RNF170 Causes Unsteady Gait with Hypertrophic Olivary Degeneration.Clinical case reports · 2026Article
- Classification of postural control characteristics during quiet standing in patients with subacute stroke and their association with lesion networks.Research square · 2026Article
- Bilateral Hypertrophic Olivary Degeneration Following Unilateral Mesencephalic Hemorrhage.Clinical case reports · 2026Article
- Hypertrophic olivary degeneration mimicking tumor recurrence after brainstem radiosurgery: A diagnostic pitfall in neuro-oncology.Surgical neurology international · 2026Article
- Multifaceted Mesodiencephalic Triangles: Insights into Hypertrophic Olivary Degeneration and Oculopalatal Tremor Pathophysiology.Cerebellum (London, England) · 2025Review
- Clinical characteristics of hypertrophic olivary degeneration following brainstem or cerebellar hemorrhage.Scientific reports · 2025Article
- Another Rare Cause of Hypertrophic Olivary Degeneration Following Cavernous Malformation Hemorrhage: A Case Report.Diagnostics (Basel, Switzerland) · 2025Article
- Hypertrophic olivary degeneration after posterior cranial fossa tumor resection in adults: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Myorhythmia: A Quantitative Study of Synchrony and Rhythmicity Between the Head and Upper Limbs.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Diaphragmatic myoclonus post cerebellar hemorrhage: a case report.BMC neurology · 2024Article
- Hypertrophic olivary degeneration secondary to a Guillain Mollaret triangle cavernoma: Two case report.Radiology case reports · 2024Article
- Monocular Torsional Oscillopsia in Dentato-olivary Disconnection.Cerebellum (London, England) · 2024Article
- Progressive ataxia and palatal tremor (PAPT) with hypertrophic olivary degeneration (HOD): A case report.Radiology case reports · 2024Article
- A Review of Ocular Movement Abnormalities in Hereditary Cerebellar Ataxias.Cerebellum (London, England) · 2024Review
- Article
- Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1.bioRxiv : the preprint server for biology · 2023Article
- Palatal myoclonus and hypertrophic olivary degeneration following wernekinck commissure syndrome: a case report.BMC neurology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertrophic degeneration of the inferior olive is mainly observed in patients developing palatal tremor (PT) or oculopalatal tremor (OPT). This syndrome manifests as a synchronous tremor of the palate (PT) and/or eyes (OPT) that may also involve other muscles from the branchial arches. It is associated with hypertrophic inferior olivary degeneration that is characterized by enlarged and vacuolated neurons, increased number and size of astrocytes, severe fibrillary gliosis, and demyelination. It appears on MRI as an increased T2/FLAIR signal intensity and enlargement of the inferior olive. There are two main conditions in which hypertrophic degeneration of the inferior olive occurs. The most frequent, studied, and reported condition is the development of PT/OPT and hypertrophic degeneration of the inferior olive in the weeks or months following a structural brainstem or cerebellar lesion. This "symptomatic" condition requires a destructive lesion in the Guillain-Mollaret pathway, which spans from the contralateral dentate nucleus
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.