SynthesisScientific reports2017
Association of wall shear stress with intracranial aneurysm rupture: systematic review and meta-analysis.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Pooled it
- Rare circle of Willis variants associated with multiple intracranial aneurysms and subarachnoid hemorrhage: A case report.Medicine · 2026Article
- Correlation between computational fluid dynamics-derived low wall shear stress and vessel wall enhancement on high-resolution MR vessel wall imaging in intracranial aneurysms.European radiology · 2026Article
- Vascular mechanical forces and vascular diseases.Journal of advanced research · 2026Review
- Physics constrained graph neural network for real time prediction of intracranial aneurysm hemodynamics.NPJ digital medicine · 2026Article
- Quantitative evaluation of computational fluid dynamics application development in the cardiovascular field through literature retrieval and bibliometric analysis.Biomedical engineering online · 2026Review
- Computational Fluid Dynamics Approaches for Analyzing Rupture and Growth of Intracranial Aneurysms: A Systematic Review.Biomedicines · 2025Review
- Mechanisms of Intracranial Aneurysm Rupture: An Integrative Review of Experimental and Clinical Evidence.Journal of clinical medicine · 2025Review
- Hemodynamic differences between intracranial and extracranial dissecting aneurysms: An analysis of shear forces and their clinical implications.Neurosurgical review · 2025Article
- Comparative performance of neurosurgery-specific, peer-reviewed versus general AI chatbots in bilingual board examinations: evaluating accuracy, consistency, and error minimization strategies.Acta neurochirurgica · 2025Article
- On the Numerical Evaluation of Wall Shear Stress Using the Finite Element Method.International journal for numerical methods in biomedical engineering · 2025Article
- Predicting Cerebral Aneurysm Rupture: The Role of Computational Fluid Dynamics.Neuroimaging clinics of North America · 2025Review
- A Review of Intracranial Aneurysm Imaging Modalities, from CT to State-of-the-Art MR.AJNR. American journal of neuroradiology · 2025Review
- Fast simulation of hemodynamics in intracranial aneurysms for clinical use.Acta neurochirurgica · 2025Article
- Effect of the Effective Metal Surface Area of Two Different Flow Diverter Stents on the Stagnation Region Formation Inside the Aneurysm Sac.Asian journal of neurosurgery · 2025Article
- Research progress in medical imaging for intracranial aneurysms: technological advances in diagnosis, management, and clinical integration.Frontiers in neurology · 2025Review
- Integrated multidisciplinary approach to aneurysm hemodynamic analysis: numerical simulation,Frontiers in bioengineering and biotechnology · 2025Review
- Computational fluid dynamics and shape analysis enhance aneurysm rupture risk stratification.International journal of computer assisted radiology and surgery · 2025Article
- Dual Approach for Basilar Artery Fenestration Aneurysm With Insights From Computational Fluid Dynamics.Neurosurgery practice · 2024Article
- Advancements in Brain Aneurysm Management: Integrating Neuroanatomy, Physiopathology, and Neurosurgical Techniques.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate the relationship between wall shear stress (WSS) magnitude and cerebral aneurysm rupture and provide new insight into the disparate computational fluid dynamics (CFD) findings concerning the role of WSS in intracranial aneurysm (IA) rupture. A systematic electronic database (PubMed, Medline, Springer, and EBSCO) search was conducted for all accessible published articles up to July 1, 2016, with no restriction on the publication year. Abstracts, full-text manuscripts, and the reference lists of retrieved articles were analyzed. Random effects meta-analysis was used to pool the complication rates across studies. Twenty-two studies containing CFD data on 1257 patients with aneurysms were included in the analysis. A significantly higher rate of low WSS (0-1.5 Pa) was found in ruptured aneurysms (odds ratio [OR] 2.17; 95% confidence interval [CI], 1.73-2.62). The pooled analyses across 14 studies with low WSS showed significantly lower mean WSS (0.64 vs. 1.4 Pa) (p = 0.037) in the ruptured group. This meta-analysis provides evidence that decreased local WSS may be an important predictive parameter of IA rupture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.