Evidence map›Paper›PMID 28706256›Full record

ArticleScientific reports2017

An extremely high dietary iodide supply forestalls severe hypothyroidism in Na

Giuseppe Ferrandino, Rachel R Kaspari, Andrea Reyna-Neyra, Nabil E Boutagy, Albert J Sinusas, Nancy Carrasco

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Gestational Exposure to Perchlorate in the Rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain.Toxicological sciences : an official journal of the Society of Toxicology · 2022
    Article
  8. Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function.Thyroid : official journal of the American Thyroid Association · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. The paradoxical lean phenotype of hypothyroid mice is marked by increased adaptive thermogenesis in the skeletal muscle.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Implications of NaJournal of the Endocrine Society · 2019
    Review
  14. Article
  15. Leptin regulation of core body temperature involves mechanisms independent of the thyroid axis.American journal of physiology. Endocrinology and metabolism · 2018
    Article
  16. Article
  17. Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Giuseppe FerrandinoDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
Rachel R KaspariDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
Andrea Reyna-NeyraDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA.
Nabil E BoutagySection of Cardiovascular Medicine, Department of Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Albert J SinusasSection of Cardiovascular Medicine, Department of Medicine, Yale School of Medicine, New Haven, CT 06510, USA.
Nancy CarrascoDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06510, USA. nancy.carrasco@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
THYROID SODIUM I/ SYMPORTERR01DK041544 · NIDDK · YESHIVA UNIVERSITY · PI ABBOTT, GEOFFREY W, CARRASCO, NANCY · 1989 to 2017
$5.6M
Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Mechanism of I- transport by the Na+/l- symporter (NIS)R01GM114250 · NIGMS · YALE UNIVERSITY · PI Nancy Carrasco · 2016 to 2026
$4.8M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL098069NIDDK NIH HHS R01 DK041544NIGMS NIH HHS R01 GM114250
6 · The paper itself

Abstract

The sodium/iodide symporter (NIS) mediates active iodide (I

Indexed as

Dietary SupplementsAnimalsBiological TransportDisease Models, AnimalHypothyroidismIodidesMice, KnockoutSodium-Iodide SymportersSymportersThyroid HormonesTreatment OutcomeIodidesSodium-Iodide SymportersSymportersThyroid Hormones

Identifiers

PMID28706256
PMCPMC5509730
OpenAlexW2726429514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.