Evidence map›Paper›PMID 28706001›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Aspirin as a COX inhibitor and anti-inflammatory drug in human skeletal muscle.

Stephen M Ratchford, Kaleen M Lavin, Ryan K Perkins, Bozena Jemiolo, Scott W Trappe, Todd A Trappe

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  7. Article
  8. Effect of Common Medications on Longitudinal Pectoralis Muscle Area in Smokers.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stephen M RatchfordHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Kaleen M LavinHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Ryan K PerkinsHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Bozena JemioloHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Scott W TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Todd A TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana.
Ball State University · US

Funding

Skeletal Muscle Health with Aging and Life-Long ExerciseR01AG038576 · NIA · BALL STATE UNIVERSITY · PI TRAPPE, SCOTT · 2011 to 2015
$1.7M
NIA NIH HHS R01 AG038576
6 · The paper itself

Abstract

Although aspirin is one of the most common anti-inflammatory drugs in the world, the effect of aspirin on human skeletal muscle inflammation is almost completely unknown. This study examined the potential effects and related time course of an orally consumed aspirin dose on the inflammatory prostaglandin E

Indexed as

AdultAnti-Inflammatory AgentsAspirinBiopsyCyclooxygenase InhibitorsDinoprostoneFemaleHumansMaleMuscle, SkeletalTissue Culture TechniquesYoung AdultAnti-Inflammatory AgentsAspirinCyclooxygenase InhibitorsDinoprostoneaspirincyclooxygenaseinflammationprostaglandin E2skeletal muscle

Identifiers

PMID28706001
PMCPMC5814685
OpenAlexW2734570255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.