Evidence map›Paper›PMID 28705898›Full record

ArticleDevelopment (Cambridge, England)2017

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.

Elisabeth A Rutledge, Jean-Denis Benazet, Andrew P McMahon

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

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  10. CRLF1 and CLCF1 in Development, Health and Disease.International journal of molecular sciences · 2022
    Review
  11. Approaches to kidney replacement therapies-opportunities and challenges.Frontiers in cell and developmental biology · 2022
    Review
  12. Article
  13. Article
  14. The epigenetic basis of cellular heterogeneity.Nature reviews. Genetics · 2021
    Review
  15. Organ-Specific Branching Morphogenesis.Frontiers in cell and developmental biology · 2021
    Review
  16. Review
  17. Article
  18. Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney.Developmental dynamics : an official publication of the American Association of Anatomists · 2020
    Article
  19. Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elisabeth A RutledgeDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0003-3540-2950
Jean-Denis BenazetDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA.
Andrew P McMahonDepartment of Stem Cell Biology and Regenerative Medicine, Eli and Edythe Broad-CIRM Center for Regenerative Medicine and Stem Cell Research, W.M. Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA amcmahon@med.usc.edu.ORCID 0000-0002-3779-1729
University of Southern California · US

Funding

Cell Interactions in Development of the Mammalian KidneyR37DK054364 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 2008 to 2017
$7.0M
CELL INTERACTIONS IN DEVELOPMENT OF THE MAMMALIAN KIDNEYR01DK054364 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCMAHON, ANDREW P. · 1998 to 2022
$6.9M
Training in Developmental Biology, Stem Cells and RegenerationT32HD060549 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Gage D Crump · 2011 to 2026
$2.5M
Characterizing Novel Regulators of Branching Morphogenesis within the Ureteric Bud TipF31DK107216 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RUTLEDGE, ELISABETH · 2015 to 2017
$112k
NICHD NIH HHS T32 HD060549NIDDK NIH HHS F31 DK107216NIDDK NIH HHS R01 DK054364NIDDK NIH HHS R37 DK054364
6 · The paper itself

Abstract

Branching morphogenesis creates arborized epithelial networks. In the mammalian kidney, an epithelial progenitor pool at ureteric branch tips (UBTs) creates the urine-transporting collecting system. Using region-specific mouse reporter strains, we performed an RNA-seq screen, identifying tip- and stalk-enriched gene sets in the developing collecting duct system. Detailed

Indexed as

OrganogenesisStem Cell NicheAnimalsGene Expression Regulation, DevelopmentalHumansIn Situ HybridizationKidneyMiceOrgan SpecificitySequence Analysis, RNAUreterBranching morphogenesisRNA-seqTip progenitorUreteric bud

Identifiers

PMID28705898
PMCPMC5611955
OpenAlexW2734632063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.