Evidence map›Paper›PMID 28705823›Full record

ArticleAJNR. American journal of neuroradiology2017

Transient Focal Neurologic Symptoms Correspond to Regional Cerebral Hypoperfusion by MRI: A Stroke Mimic in Children.

L L Lehman, A R Danehy, C C Trenor, C F Calahan, M E Bernson-Leung, R L Robertson, M J Rivkin

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

L L LehmanFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0002-6007-0356
A R DanehyFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0003-4077-9971
C C TrenorFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0003-3954-7882
C F CalahanFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0002-9631-8966
M E Bernson-LeungFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0002-7766-2323
R L RobertsonRadiology (A.R.D., R.L.R., M.J.R.) richard.robertson@childerns.harvard.edu.ORCID http://orcid.org/0000-0001-8811-4405
M J RivkinFrom the Stroke and Cerebrovascular Center (L.L.L., A.R.D., C.C.T., C.F.C., M.E.B.-L., M.J.R.).ORCID http://orcid.org/0000-0003-3013-7107
United States Nuclear Regulatory Commission · USBoston Children's Hospital · USRCA (United States) · USRobert Morris University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children who present with acute transient focal neurologic symptoms raise concern for stroke or transient ischemic attack. We present a series of 16 children who presented with transient focal neurologic symptoms that raised concern for acute stroke but who had no evidence of infarction and had unilateral, potentially reversible imaging features on vascular and perfusion-sensitive brain MR imaging. Patients were examined with routine brain MR imaging, MRA, perfusion-sensitive sequences, and DWI. Fourteen (88%) children had lateralized MRA evidence of arterial tree pruning without occlusion, all had negative DWI findings, and all showed evidence of hemispheric hypoperfusion by susceptibility-weighted imaging or arterial spin-labeling perfusion imaging at presentation. These findings normalized following resolution of symptoms in all children who had follow-up imaging (6/16, 38%). The use of MR imaging with perfusion-sensitive sequences, DWI, and MRA can help to rapidly distinguish children with conditions mimicking stroke from those with acute stroke.

Indexed as

AgedBrainCerebrovascular CirculationChildFemaleHumansIschemic Attack, TransientMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPerfusion ImagingStroke

Identifiers

PMID28705823
PMCPMC7963593
OpenAlexW2734456261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.