Evidence map›Paper›PMID 28705810›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

The butyrophilin 3A1 intracellular domain undergoes a conformational change involving the juxtamembrane region.

Khiem Nguyen, Jin Li, Robbins Puthenveetil, Xiaochen Lin, Michael M Poe, Chia-Hung Christine Hsiao, Olga Vinogradova, Andrew J Wiemer

Erratum issuedAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Cell stress activates γ9δ2 T cells via endogenous phosphoantigens and butyrophilin complex dynamics.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
    Article
  3. Review
  4. Investigation of structural and dynamic properties of the Butyrophilin BTN3A1/BTN2A1 cytoplasmic complex byFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Up-regulation of BTN3A1 on CD14Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Potent double prodrug forms of synthetic phosphoantigens.Bioorganic & medicinal chemistry · 2020
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Khiem NguyenDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Jin LiDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Robbins PuthenveetilDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Xiaochen LinDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Michael M PoeDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Chia-Hung Christine HsiaoDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Olga VinogradovaDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA.
Andrew J WiemerDepartment of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut, USA; andrew.wiemer@uconn.edu.
University of Connecticut · US

Funding

Regulation of gamma delta T cell immunoediting by novel phosphoantigensR01CA186935 · NCI · UNIVERSITY OF CONNECTICUT STORRS · PI WIEMER, ANDREW J · 2015 to 2018
$1.5M
NCI NIH HHS R01 CA186935
6 · The paper itself

Abstract

Small isoprenoid diphosphates, such as (

Indexed as

Amino Acid SubstitutionAntigens, CDButyrophilinsHumansK562 CellsMutation, MissenseNuclear Magnetic Resonance, BiomolecularOrganophosphatesProtein DomainsX-Ray Diffraction4-hydroxy-3-methyl-2-butenyl diphosphateAntigens, CDBTN3A1 protein, humanButyrophilinsOrganophosphatesB7 family coreceptorbisphosphonateCD277phosphoantigenγ δ T cell

Identifiers

PMID28705810
PMCPMC5636706
OpenAlexW2735786303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.