ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2017
Whole-genome characterization of Uruguayan strains of avian infectious bronchitis virus reveals extensive recombination between the two major South American lineages.
Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 25 citations in OpenAlex.
- Comparative pathogenicity of Ma5 vaccine and a field isolate of the avian infectious bronchitis virus in SPF chickens.Poultry science · 2026Article
- Thirty-Five Years of IBV Evolution in Chile Reveals a Novel Lineage and Evidence of Vaccine-Driven Recombination.Viruses · 2025Article
- Article
- Genetic Analysis of Infectious Bronchitis Virus S1 Gene Reveals Novel Amino Acid Changes in the GI-16 Lineage in Peru.Microorganisms · 2023Article
- New Insights into Avian Infectious Bronchitis Virus in Colombia from Whole-Genome Analysis.Viruses · 2022Article
- Origin of New Lineages by Recombination and Mutation in Avian Infectious Bronchitis Virus from South America.Viruses · 2022Article
- Novel Lineage of Infectious Bronchitis Virus from Sub-Saharan Africa Identified by Random Amplification and Next-Generation Sequencing of Viral Genome.Life (Basel, Switzerland) · 2022Article
- Emergence of Avian coronavirus genotype GI-11 in Colombia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- The taxonomy, host range and pathogenicity of coronaviruses and other viruses in theAnimal diseases · 2021Review
- Animal Coronaviruses in the Light of COVID-19.Journal of veterinary research · 2020Review
- Epigenetic Regulation by Non-Coding RNAs in the Avian Immune System.Life (Basel, Switzerland) · 2020Review
- Synanthropic rodents as virus reservoirs and transmitters.Revista da Sociedade Brasileira de Medicina Tropical · 2020Review
- Attenuation of Infectious Bronchitis Virus in Eggs Results in Different Patterns of Genomic Variation across Multiple Replicates.Journal of virology · 2019Article
- Microarray analysis of infectious bronchitis virus infection of chicken primary dendritic cells.BMC genomics · 2019Article
- Molecular characterization of whole genome sequence of infectious bronchitis virus 624I genotype confirms the close relationship with Q1 genotype.Transboundary and emerging diseases · 2019Article
- Near-Complete Genome Sequence of Infectious Bronchitis Virus Strain VFAR-047 (GI-16 Lineage), Isolated in Peru.Microbiology resource announcements · 2019Article
- GI-16 lineage (624/I or Q1), there and back again: The history of one of the major threats for poultry farming of our era.PloS one · 2018Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infectious bronchitis virus (Gammacoronavirus, Coronaviridae) is a genetically variable RNA virus that causes one of the most persistent respiratory diseases in poultry. The virus is classified in genotypes and lineages with different epidemiological relevance. Two lineages of the GI genotype (11 and 16) have been widely circulating for decades in South America. GI-11 is an exclusive South American lineage while the GI-16 lineage is distributed in Asia, Europe and South America. Here, we obtained the whole genome of two Uruguayan strains of the GI-11 and GI-16 lineages using Illumina high-throughput sequencing. The strains here sequenced are the first obtained in South America for the infectious bronchitis virus and provide new insights into the origin, spreading and evolution of viral variants. The complete genome of the GI-11 and GI-16 strains have 27,621 and 27,638 nucleotides, respectively, and possess the same genomic organization. Phylogenetic incongruence analysis reveals that both strains have a mosaic genome that arose by recombination between Euro Asiatic strains of the GI-16 lineage and ancestral South American GI-11 viruses. The recombination occurred in South America and produced two viral variants that have retained the full-length S1 sequences of the parental lineages but are extremely similar in the rest of their genomes. These recombinant virus have been extraordinary successful, persisting in the continent for several years with a notorious wide geographic distribution. Our findings reveal a singular viral dynamics and emphasize the importance of complete genomic characterization to understand the emergence and evolutionary history of viral variants.
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