Evidence map›Paper›PMID 28705490›Full record

Trial reportSurgery2017

Deformation correction for image guided liver surgery: An intraoperative fidelity assessment.

Logan W Clements, Jarrod A Collins, Jared A Weis, Amber L Simpson, T Peter Kingham, William R Jarnagin, Michael I Miga

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Navigated hepatic tumor resection using intraoperative ultrasound imaging.International journal of computer assisted radiology and surgery · 2026
    Article
  2. Article
  3. Article
  4. Registration Sanity Check for AR-guided Surgical Interventions: Experience From Head and Face Surgery.IEEE journal of translational engineering in health and medicine · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Augmented Reality during Open Liver Surgery Using a Markerless Non-rigid Registration System.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  9. Article
  10. Estimation of boundary conditions for patient-specific liver simulation during augmented surgery.International journal of computer assisted radiology and surgery · 2020
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Logan W ClementsDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN. Electronic address: logan.clements@vanderbilt.edu.
Jarrod A CollinsDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.
Jared A WeisDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.
Amber L SimpsonDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.
T Peter KinghamDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.
William R JarnaginDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.
Michael I MigaDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN.

Funding

Multimodal Registration of the Brain's Cortical SurfaceR01NS049251 · NINDS · VANDERBILT UNIVERSITY · PI GOLBY, ALEXANDRA J, MIGA, MICHAEL IAN · 2005 to 2018
$6.7M
Clinical Translation of Deformation Compensation for Image-Guided Liver SurgeryR01CA162477 · NCI · VANDERBILT UNIVERSITY · PI JARNAGIN, WILLIAM ROBERT, MIGA, MICHAEL IAN · 2011 to 2015
$3.0M
NCI NIH HHS R01 CA162477NINDS NIH HHS R01 NS049251
6 · The paper itself

Abstract

backgroundAlthough systems of 3-dimensional image-guided surgery are a valuable adjunct across numerous procedures, differences in organ shape between that reflected in the preoperative image data and the intraoperative state can compromise the fidelity of such guidance based on the image. In this work, we assessed in real time a novel, 3-dimensional image-guided operation platform that incorporates soft tissue deformation.

methodsA series of 125 alignment evaluations were performed across 20 patients. During the operation, the surgeon assessed the liver by swabbing an optically tracked stylus over the liver surface and viewing the image-guided operation display. Each patient had approximately 6 intraoperative comparative evaluations. For each assessment, 1 of only 2 types of alignments were considered: conventional rigid and novel deformable. The series of alignment types used was randomized and blinded to the surgeon. The surgeon provided a rating, R, from -3 to +3 for each display compared with the previous display, whereby a negative rating indicated degradation in fidelity and a positive rating an improvement.

resultsA statistical analysis of the series of rating data by the clinician indicated that the surgeons were able to perceive an improvement (defined as a R > 1) of the model-based registration over the rigid registration (P = .01) as well as a degradation (defined as R < -1) when the rigid registration was compared with the novel deformable guidance information (P = .03).

conclusionThis study provides evidence of the benefit of deformation correction in providing an accurate location for the liver for use in image-guided surgery systems.

Indexed as

Imaging, Three-DimensionalAdultAgedFemaleFollow-Up StudiesHepatectomyHumansLiverLiver NeoplasmsMaleMiddle AgedMonitoring, IntraoperativeOutcome Assessment, Health CareSingle-Blind MethodStatistics, NonparametricSurgery, Computer-Assisted

Identifiers

PMID28705490
PMCPMC5836469

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.