Evidence map›Paper›PMID 28704927›Full record

ReviewBiomolecules2017

The TOR Signaling Network in the Model Unicellular Green Alga Chlamydomonas reinhardtii.

María Esther Pérez-Pérez, Inmaculada Couso, José L Crespo

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 81 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Sugar signals pedal the cell cycle!Frontiers in plant science · 2024
    Review
  10. Article
  11. Article
  12. Target of Rapamycin Regulates Photosynthesis and Cell Growth inInternational journal of molecular sciences · 2022
    Article
  13. Article
  14. Role of Autophagy inPlants (Basel, Switzerland) · 2022
    Article
  15. Photosynthetic assimilation of COProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

María Esther Pérez-PérezInstituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad de Sevilla, Avda. Américo Vespucio 49, Sevilla 41092, Spain. eperez@ibvf.csic.es.
Inmaculada CousoInstituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad de Sevilla, Avda. Américo Vespucio 49, Sevilla 41092, Spain. inmaculada.couso@ibvf.csic.es.
José L CrespoInstituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas (CSIC)-Universidad de Sevilla, Avda. Américo Vespucio 49, Sevilla 41092, Spain. crespo@ibvf.csic.es.
Consejo Superior de Investigaciones Científicas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell growth is tightly coupled to nutrient availability. The target of rapamycin (TOR) kinase transmits nutritional and environmental cues to the cellular growth machinery. TOR functions in two distinct multiprotein complexes, termed TOR complex 1 (TORC1) and TOR complex 2 (TORC2). While the structure and functions of TORC1 are highly conserved in all eukaryotes, including algae and plants, TORC2 core proteins seem to be missing in photosynthetic organisms. TORC1 controls cell growth by promoting anabolic processes, including protein synthesis and ribosome biogenesis, and inhibiting catabolic processes such as autophagy. Recent studies identified rapamycin-sensitive TORC1 signaling regulating cell growth, autophagy, lipid metabolism, and central metabolic pathways in the model unicellular green alga

Indexed as

Algal ProteinsAutophagyChlamydomonas reinhardtiiGene Expression Regulation, FungalLipid MetabolismMechanistic Target of Rapamycin Complex 1Mechanistic Target of Rapamycin Complex 2PhotosynthesisProtein BiosynthesisAlgal ProteinsMechanistic Target of Rapamycin Complex 1Mechanistic Target of Rapamycin Complex 2algaeautophagyChlamydomonasFKBP12lipid metabolismrapamycintarget of rapamycin (TOR)

Identifiers

PMID28704927
PMCPMC5618235
OpenAlexW2735249862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.