ArticlePloS one2017
Genetic mapping of the LOBED LEAF 1 (ClLL1) gene to a 127.6-kb region in watermelon (Citrullus lanatus L.).
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Speed breeding enhances crop resilience and productivity in a changing climate.Molecular breeding : new strategies in plant improvement · 2025Review
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- Discovery of variation in genes related to agronomic traits by sequencing the genome of Cucurbita pepo varieties.BMC genomics · 2025Article
- Fine mapping and identification of the geneFrontiers in plant science · 2025Article
- Identification of Chromosomal Regions and Candidate Genes forPlants (Basel, Switzerland) · 2024Article
- Creation of a watermelon haploid inducer line viaHorticulture research · 2023Article
- BSR and Full-Length Transcriptome Approaches Identified Candidate Genes for High Seed Ratio inCurrent issues in molecular biology · 2022Article
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- The upregulated LsKN1 gene transforms pinnately to palmately lobed leaves through auxin, gibberellin, and leaf dorsiventrality pathways in lettuce.Plant biotechnology journal · 2022Article
- Development and Application of InDel Markers Linked to Fruit-Shape and Peel-Colour Genes in Wax Gourd.Genes · 2022Article
- Promoter variation in a homeobox gene, CpDll, is associated with deeply lobed leaf in Cucurbita pepo L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Understanding the molecular mechanism of leaf morphogenesis in vegetable crops conduces to breeding process.Frontiers in plant science · 2022Review
- Genetic Analysis of Fruit Quality Traits in Sweet Watermelon (Frontiers in plant science · 2022Review
- The branchless gene Clbl in watermelon encoding a TERMINAL FLOWER 1 protein regulates the number of lateral branches.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Candidate gene analysis of watermelon stripe pattern locus ClSP ongoing recombination suppression.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Construction of a High-Density Genetic Map and Identification of Leaf Trait-Related QTLs in Chinese Bayberry (Frontiers in plant science · 2021Article
- A mutation in the intron splice acceptor site of a GA3ox gene confers dwarf architecture in watermelon (Citrullus lanatus L.).Scientific reports · 2020Article
- Fine mapping and identification of the leaf shape gene BoFL in ornamental kale.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- Ethylene-responsive factor 4 is associated with the desirable rind hardness trait conferring cracking resistance in fresh fruits of watermelon.Plant biotechnology journal · 2020Article
- A Single Nucleotide Deletion in an ABC Transporter Gene Leads to a Dwarf Phenotype in Watermelon.Frontiers in plant science · 2019Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The lobed leaf character is a unique morphologic trait in crops, featuring many potential advantages for agricultural productivity. Although the majority of watermelon varieties feature lobed leaves, the genetic factors responsible for lobed leaf formation remain elusive. The F2:3 leaf shape segregating population offers the opportunity to study the underlying mechanism of lobed leaf formation in watermelon. Genetic analysis revealed that a single dominant allele (designated ClLL1) controlled the lobed leaf trait. A large-sized F3:4 population derived from F2:3 individuals was used to map ClLL1. A total of 5,966 reliable SNPs and indels were identified genome-wide via a combination of BSA and RNA-seq. Using the validated SNP and indel markers, the location of ClLL1 was narrowed down to a 127.6-kb region between markers W08314 and W07061, containing 23 putative ORFs. Expression analysis via qRT-PCR revealed differential expression patterns (fold-changes above 2-fold or below 0.5-fold) of three ORFs (ORF3, ORF11, and ORF18) between lobed and non-lobed leaf plants. Based on gene annotation and expression analysis, ORF18 (encoding an uncharacterized protein) and ORF22 (encoding a homeobox-leucine zipper-like protein) were considered as most likely candidate genes. Furthermore, sequence analysis revealed no polymorphisms in cDNA sequences of ORF18; however, two notable deletions were identified in ORF22. This study is the first report to map a leaf shape gene in watermelon and will facilitate cloning and functional characterization of ClLL1 in future studies.
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