Evidence map›Paper›PMID 28704494›Full record

ArticlePloS one2017

Effects of a multidisciplinary weight loss intervention in overweight and obese children and adolescents: 11 years of experience.

Chiara Mameli, Jesse C Krakauer, Nir Y Krakauer, Alessandra Bosetti, Chiara Matilde Ferrari, Laura Schneider, Barbara Borsani, Sara Arrigoni, Erica Pendezza, Gian Vincenzo Zuccotti

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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  16. NAFLD in children: new genes, new diagnostic modalities and new drugs.Nature reviews. Gastroenterology & hepatology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Chiara MameliDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Jesse C KrakauerMetro Detroit Diabetes and Endocrinology, Southfield, MI, United States of America.
Nir Y KrakauerDepartment of Civil Engineering, The City College of New York, New York, NY, United States of America.
Alessandra BosettiDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Chiara Matilde FerrariDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Laura SchneiderDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Barbara BorsaniDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Sara ArrigoniDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Erica PendezzaDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
Gian Vincenzo ZuccottiDepartment of Pediatrics, V.Buzzi Childrens' Hospital, University of Milan, Milan, Italy.
University of Milan · ITCity College of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate the effects of an outpatient multidisciplinary weight loss intervention in reducing body mass index (BMI) in children and adolescents suffering overweight and obesity, changes in A Body Shape Index (ABSI, waist circumference normalized to height and weight) and Hip Index (HI, normalized hip circumference) during treatment and correlation between the ABSI and HI with change in BMI z score.

methodsWe analyze anthropometric data from pediatric patients affected by overweight and obesity aged 2 to 18 years old who entered our multidisciplinary weight loss intervention, which included medical, psychological and nutritional sessions, from January 1st 2006 to December 31st 2016. Lifestyle modification counselling was delivered. Follow-up visits were planned every month for 3 months and subsequently every 2-4 months. BMI, ABSI, and HI were converted to z scores using age and sex specific population normals.

results864 patients entered our intervention. 453 patients (208 males), mean age 11.2 ±3.1 years, 392 with obesity (86%, z-BMI 2.90 ±0.80 SD) and 61 patients with overweight (z-BMI 1.73±0.21 SD) attended at least 1 follow-up visit. The mean number of visits was 3.5 (± 1.8 SD) in overweight subjects and 3.9 (±2.2 SD) in ones with obesity. At the last attended follow-up visit (at 16 ± 12 months SD) we observed a reduction in mean z-BMI in patients with obesity (to 2.52 ±0.71 SD) and patients with overweight (to 1.46 ±0.5 SD). Most patients (80.8%) reduced their BMI z scores. Mean ABSI and HI z scores showed no significant change. 78/392 patients (19.8%) recovered from obese to overweight, 5/392 (1.2%) from obese to normal weight. The recovery rate from overweight to normal weight was 13.1%. In a multivariate model, initial BMI z score and number of follow-up visits were significant predictors of weight change, while age, sex, ABSI, and HI were not significant predictors.

conclusionsPatients affected by overweight and obesity involved in a multidisciplinary weight loss intervention reduced their mean BMI z score, while ABSI and HI were stable. Weight loss was not predicted by initial ABSI or HI. More visits predict more weight loss, but dropout rates are high. The great majority of patients leave the weight management program before having normalized their BMI.

Indexed as

AdolescentAmbulatory CareAnthropometryBody Mass IndexChildChild, PreschoolFemaleHumansMaleNutrition AssessmentOverweightPediatric ObesityTreatment OutcomeWaist CircumferenceWeight LossWeight Reduction Programs

Identifiers

PMID28704494
PMCPMC5509286
OpenAlexW2734761064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.