Evidence map›Paper›PMID 28704468›Full record

ArticlePloS one2017

ThMYC4E, candidate Blue aleurone 1 gene controlling the associated trait in Triticum aestivum.

Na Li, Shiming Li, Kunpu Zhang, Wenjie Chen, Bo Zhang, Daowen Wang, Dengcai Liu, Baolong Liu, Huaigang Zhang

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Frontiers in plant science · 2021
    Article
  4. Article
  5. Article
  6. Overexpression ofInternational journal of molecular sciences · 2019
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Na LiQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.
Shiming LiQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.
Kunpu ZhangState Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Development Biology, Chinese Academy of Sciences, Beijing, China.
Wenjie ChenQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.
Bo ZhangQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.
Daowen WangState Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Development Biology, Chinese Academy of Sciences, Beijing, China.
Dengcai LiuTriticeae Research Institute, Sichuan Agricultural University, Chengdu, Sichuan, China.
Baolong LiuQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.ORCID http://orcid.org/0000-0002-6756-4033
Huaigang ZhangQinghai Province Key Laboratory of Crop Molecular Breeding, Xining, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blue aleurone is a useful and interesting trait in common wheat that was derived from related species. Here, transcriptomes of blue and white aleurone were compared for isolating Blue aleurone 1 (Ba1) transferred from Thinopyrum ponticum. In the genes involved in anthocyanin biosynthesis, only a basic helix-loop-helix (bHLH) transcription factor, ThMYC4E, had a higher transcript level in blue aleurone phenotype, and was homologous to the genes on chromosome 4 of Triticum aestivum. ThMYC4E carried the characteristic domains (bHLH-MYC_N, HLH and ACT-like) of a bHLH transcription factor, and clustered with genes regulating anthocyanin biosynthesis upon phylogenetic analysis. The over-expression of ThMYC4E regulated anthocyanin biosynthesis with the coexpression of the MYB transcription factor ZmC1 from maize. ThMYC4E existed in the genomes of the addition, substitution and near isogenic lines with the blue aleurone trait derived from Th. ponticum, and could not be detected in any germplasm of T. urartu, T. monococcum, T. turgidum, Aegilops tauschii or T. aestivum, with white aleurone. These results suggested that ThMYC4E was candidate Ba1 gene controlling the blue aleurone trait in T. aestivum genotypes carrying Th. ponticum introgression. The ThMYC4E isolation aids in better understanding the genetic mechanisms of the blue aleurone trait and in its more effective use during wheat breeding.

Indexed as

AnthocyaninsBasic Helix-Loop-Helix ProteinsCloning, MolecularGene Expression ProfilingGenes, PlantPhylogenyQuantitative Trait LociSequence Analysis, RNATriticumAnthocyaninsBasic Helix-Loop-Helix Proteins

Identifiers

PMID28704468
PMCPMC5509306

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.