Observational studyPloS one2017
Variations in achievement of evidence-based, high-impact quality indicators in general practice: An observational study.
Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Quality of care for people with chronic kidney disease: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Quality indicators for the primary prevention of cardiovascular disease in primary care: A systematic review.PloS one · 2024Pooled it
- Sex Disparities in Cardiovascular Risk Factor Assessment and Screening for Diabetes-Related Complications in Individuals With Diabetes: A Systematic Review.Frontiers in endocrinology · 2021Pooled it
- The Role of Physician and Practice Characteristics in the Quality of Diabetes Management in Primary Care: Systematic Review and Meta-analysis.Journal of general internal medicine · 2020Pooled it
- An adaptable implementation package targeting evidence-based indicators in primary care: A pragmatic cluster-randomised evaluation.PLoS medicine · 2020Trial
- Chronic kidney disease in older adults: trends in prevalence and healthcare service quality from 2012 to 2018.Clinical kidney journal · 2025Article
- Interventions to improve the implementation of evidence-based healthcare in prisons: a scoping review.Health & justice · 2023Article
- Finding Primary Care-Repurposing Physician Registration Data to Generate a Regionally Accurate List of Primary Care Clinics: Development and Validation of an Open-Source Algorithm.JMIR formative research · 2022Article
- Quality indicators and performance measures for prison healthcare: a scoping review.Health & justice · 2022Article
- Quality and variation of care for chronic kidney disease in Swiss general practice: A retrospective database study.PloS one · 2022Article
- Multiplicity and complexity: a qualitative exploration of influences on prescribing in UK general practice.BMJ open · 2021Article
- Article
- Changes in patient experience associated with growth and collaboration in general practice: observational study using data from the UK GP Patient Survey.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Observational
- Sex differences in the risk of vascular disease associated with diabetes.Biology of sex differences · 2020Review
- How widespread is working at scale in English general practice? An observational study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Observational
- Quality improvement of prescribing safety: a pilot study in primary care using UK electronic health records.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Protocol for a mixed methods realist evaluation of regional District Health Board groupings in New Zealand.BMJ open · 2019Article
- Article
- Timings for HbADiabetic medicine : a journal of the British Diabetic Association · 2019Article
- Influence of patient characteristics on preventive service delivery and general practitioners' preventive performance indicators: A study in patients with hypertension or diabetes mellitus from Hungary.The European journal of general practice · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThere are widely recognised variations in the delivery and outcomes of healthcare but an incomplete understanding of their causes. There is a growing interest in using routinely collected 'big data' in the evaluation of healthcare. We developed a set of evidence-based 'high impact' quality indicators (QIs) for primary care and examined variations in achievement of these indicators using routinely collected data in the United Kingdom (UK).
methodsCross-sectional analysis of routinely collected, electronic primary care data from a sample of general practices in West Yorkshire, UK (n = 89). The QIs covered aspects of care (including processes and intermediate clinical outcomes) in relation to diabetes, hypertension, atrial fibrillation, myocardial infarction, chronic kidney disease (CKD) and 'risky' prescribing combinations. Regression models explored the impact of practice and patient characteristics. Clustering within practice was accounted for by including a random intercept for practice.
resultsMedian practice achievement of the QIs ranged from 43.2% (diabetes control) to 72.2% (blood pressure control in CKD). Considerable between-practice variation existed for all indicators: the difference between the highest and lowest performing practices was 26.3 percentage points for risky prescribing and 100 percentage points for anticoagulation in atrial fibrillation. Odds ratios associated with the random effects for practices emphasised this; there was a greater than ten-fold difference in the likelihood of achieving the hypertension indicator between the lowest and highest performing practices. Patient characteristics, in particular age, gender and comorbidity, were consistently but modestly associated with indicator achievement. Statistically significant practice characteristics were identified less frequently in adjusted models.
conclusionsDespite various policy and improvement initiatives, there are enduring inappropriate variations in the delivery of evidence-based care. Much of this variation is not explained by routinely collected patient or practice variables, and is likely to be attributable to differences in clinical and organisational behaviour.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.