Observational studyInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2017
Single Marital Status and Infectious Mortality in Women With Cervical Cancer in the United States.
Observational study in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Disparities in Human Papillomavirus Vaccination and Cervical Cancer Prevention and Screening Strategies: A Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- Single status shows age dependent bidirectional effects in differentiated thyroid cancer.Scientific reports · 2025Article
- Transcriptome profiling revealed multiple circadian rhythm-related genes associated with common gynecological cancers.Frontiers in oncology · 2025Article
- Prevalence of cervical intraepithelial lesions and associated factors among women attending a cervical cancer clinic in Western Uganda; results based on Pap smear cytology.SAGE open medicine · 2024Article
- Real-world implications of nonbiological factors with staging, clinical management, and prognostic prediction in pancreatic ductal adenocarcinoma.Cancer medicine · 2023Article
- A model established using marital status and other factors from the Surveillance, Epidemiology, and End Results database for early stage gastric cancer.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022Article
- Fatal Infections Among Cancer Patients: A Population-Based Study in the United States.Infectious diseases and therapy · 2021Article
- Survival and prognostic factors in primary vaginal cancer: an analysis of 2004-2014 SEER data.Translational cancer research · 2020Article
- Mortality from cervical cancer in Brazil: an ecological epidemiologic study of a 22-year analysis.Ecancermedicalscience · 2020Article
- Trends in single women with malignancy of the uterine cervix in United States.Journal of gynecologic oncology · 2018Observational
- The Infection Status and Distribution of hrHPV in Cervical Lesions Among Overweight Women Referred for Colposcopy: A Cross-Sectional Study.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveUnmarried status including single marital status is associated with increased mortality in women bearing malignancy. Infectious disease weights a significant proportion of mortality in patients with malignancy. Here, we examined an association of single marital status and infectious mortality in cervical cancer.
methodsThis is a retrospective observational study examining 86,555 women with invasive cervical cancer identified in the Surveillance, Epidemiology, and End Results Program between 1973 and 2013. Characteristics of 18,324 single women were compared with 38,713 married women in multivariable binary logistic regression models. Propensity score matching was performed to examine cumulative risk of all-cause and infectious mortality between the 2 groups.
resultsSingle marital status was significantly associated with young age, black/Hispanic ethnicity, Western US residents, uninsured status, high-grade tumor, squamous histology, and advanced-stage disease on multivariable analysis (all, P < 0.05). In a prematched model, single marital status was significantly associated with increased cumulative risk of all-cause mortality (5-year rate: 32.9% vs 29.7%, P < 0.001) and infectious mortality (0.5% vs 0.3%, P < 0.001) compared with the married status. After propensity score matching, single marital status remained an independent prognostic factor for increased cumulative risk of all-cause mortality (adjusted hazards ratio [HR], 1.15; 95% confidence interval [CI], 1.11-1.20; P < 0.001) and those of infectious mortality on multivariable analysis (adjusted HR, 1.71; 95% CI, 1.27-2.32; P < 0.001). In a sensitivity analysis for stage I disease, single marital status remained significantly increased risk of infectious mortality after propensity score matching (adjusted HR, 2.24; 95% CI, 1.34-3.73; P = 0.002).
conclusionsSingle marital status was associated with increased infectious mortality in women with invasive cervical cancer.
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