Evidence map›Paper›PMID 28703771›Full record

ReviewViruses2017

Vertebrate Reservoirs of Arboviruses: Myth, Synonym of Amplifier, or Reality?

Goro Kuno, John S Mackenzie, Sandra Junglen, Zdeněk Hubálek, Alexander Plyusnin, Duane J Gubler

Abstract readReview
In one paragraph

Review in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Australian vertebrate hosts of Japanese encephalitis virus: a review of the evidence.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Goro KunoFormerly at the Division of Vector-Borne Infectious Diseases, Centers for Control and Prevention, Fort Collins, CO, USA. gykuno@gmail.com.
John S MackenzieFaculty of Medical Sciences, Curtin University, GPO Box U1987, Perth, WA 6845, Australia. j.mackenzie@curtin.edu.au.
Sandra JunglenInstitute of Virology, Charité-Universitätsmedizin Berlin, Helmut-Ruska-Haus, Chariteplatz 1, 10117 Berlin, Germany. sandra.junglen@charite.de.
Zdeněk HubálekInstitute of Vertebrate Biology, Academy of Sciences of Czech Republic, 60365 Brno, Czech Republic. zhubalek@brno.cas.cz.
Alexander PlyusninDepartment of Virology, University of Helsinki, Haartmaninkatu 3, University of Helsinki, 00014 Helsinki, Finland. Alexander.Plyusnin@Helsinki.Fi.
Duane J GublerProgram in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Rd., Singapore 169857 Singapore. duane.gubler@duke-nus.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid succession of the pandemic of arbovirus diseases, such as dengue, West Nile fever, chikungunya, and Zika fever, has intensified research on these and other arbovirus diseases worldwide. Investigating the unique mode of vector-borne transmission requires a clear understanding of the roles of vertebrates. One major obstacle to this understanding is the ambiguity of the arbovirus definition originally established by the World Health Organization. The paucity of pertinent information on arbovirus transmission at the time contributed to the notion that vertebrates played the role of reservoir in the arbovirus transmission cycle. Because this notion is a salient feature of the arbovirus definition, it is important to reexamine its validity. This review addresses controversial issues concerning vertebrate reservoirs and their role in arbovirus persistence in nature, examines the genesis of the problem from a historical perspective, discusses various unresolved issues from multiple points of view, assesses the present status of the notion in light of current knowledge, and provides options for a solution to resolve the issue.

Indexed as

AnimalsArbovirusesArbovirus InfectionsCulicidaeDengueDisease ReservoirsHost SpecificityHumansMiceVertebratesWest Nile FeverZika Virus InfectionZoonosesarbovirushost rangeinsect-specific virusorigin of arbovirustransmission mechanismvertebrate reservoirvirus maintenancezoonosis

Identifiers

PMID28703771
PMCPMC5537677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.