Evidence map›Paper›PMID 28703767›Full record

ReviewMolecules (Basel, Switzerland)2017

Co-Transcriptional Folding and Regulation Mechanisms of Riboswitches.

Sha Gong, Yanli Wang, Zhen Wang, Wenbing Zhang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Landscape Zooming toward the Prediction of RNA Cotranscriptional Folding.Journal of chemical theory and computation · 2022
    Article
  14. Article
  15. Alternate RNA Structures.Cold Spring Harbor perspectives in biology · 2020
    Review
  16. Article
  17. Review
  18. Predicting Cotranscriptional Folding Kinetics For Riboswitch.The journal of physical chemistry. B · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sha GongHubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains, Huanggang Normal University, Huanggang 438000, Hubei, China. shagong@hgnu.edu.cn.
Yanli WangDepartment of Physics, Wuhan University, Wuhan 430072, Hubei, China. 13212746736@163.com.
Zhen WangDepartment of Physics, Wuhan University, Wuhan 430072, Hubei, China. zhenwang@whu.edu.cn.
Wenbing ZhangDepartment of Physics, Wuhan University, Wuhan 430072, Hubei, China. wbzhang@whu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Riboswitches are genetic control elements within non-coding regions of mRNA. These self-regulatory elements have been found to sense a range of small metabolites, ions, and other physical signals to exert regulatory control of transcription, translation, and splicing. To date, more than a dozen riboswitch classes have been characterized that vary widely in size and secondary structure. Extensive experiments and theoretical studies have made great strides in understanding the general structures, genetic mechanisms, and regulatory activities of individual riboswitches. As the ligand-dependent co-transcriptional folding and unfolding dynamics of riboswitches are the key determinant of gene expression, it is important to investigate the thermodynamics and kinetics of riboswitches both in the presence and absence of metabolites under the transcription. This review will provide a brief summary of the studies about the regulation mechanisms of the

Indexed as

RNA FoldingTranscription, GeneticGene Expression RegulationKineticsLigandsNucleic Acid ConformationRiboswitchRNA, MessengerThermodynamicsLigandsRiboswitchRNA, Messengerco-transcriptional foldinggene regulationriboswitch

Identifiers

PMID28703767
PMCPMC6152003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.