Evidence map›Paper›PMID 28703766›Full record

ArticleMolecules (Basel, Switzerland)2017

Synthesis and In Vitro Antimycobacterial and Antibacterial Activity of 8-OMe Ciprofloxacin-Hydrozone/Azole Hybrids.

Zhi Xu, Shu Zhang, Lian-Shun Feng, Xiao-Ning Li, Guo-Cheng Huang, Yun Chai, Zao-Sheng Lv, Hui-Yuan Guo, Ming-Liang Liu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhi XuKey Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, Wuhan University of Science and Technology, Wuhan 430081, China. chemorgchem@126.com.
Shu ZhangPony Testing International Group (Wuhan), Wuhan 430000, China. zhangshu-zs@163.com.
Lian-Shun FengInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. ochemistry@163.com.
Xiao-Ning LiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. whorgchem@126.com.
Guo-Cheng HuangKey Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, Wuhan University of Science and Technology, Wuhan 430081, China. drugscience@163.com.
Yun ChaiInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. chemmedchem@163.com.
Zao-Sheng LvKey Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, Wuhan University of Science and Technology, Wuhan 430081, China. whmedchem@126.com.
Hui-Yuan GuoInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. guohuiyuan108@126.com.
Ming-Liang LiuInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. lvzaosheng@wust.edu.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNWuhan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel 8-OMe ciprofloxacin (CPFX)-hydrazone/azole hybrids were designed, synthesized, and evaluated for their in vitro biological activities. Our results reveal that all of the hydrozone-containing hybrids (except for

Indexed as

AnimalsAnti-Bacterial AgentsAntitubercular AgentsAzolesCiprofloxacinHumansHydrozoaMicrobial Sensitivity TestsMycobacterium tuberculosisTuberculosisAnti-Bacterial AgentsAntitubercular AgentsAzolesCiprofloxacin8-OMe ciprofloxacinantibacterialantimycobacterialhybridssynthesis

Identifiers

PMID28703766
PMCPMC6152256
OpenAlexW2736181592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.