Evidence map›Paper›PMID 28703729›Full record

ArticleSexually transmitted diseases2017

A Case of Decreased Susceptibility to Ceftriaxone in Neisseria gonorrhoeae in the Absence of a Mosaic Penicillin-Binding Protein 2 (penA) Allele.

A Jeanine Abrams, Robert D Kirkcaldy, Kevin Pettus, Jan L Fox, Grace Kubin, David L Trees

Abstract readCase Reports
In one paragraph

Article in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Point-by-Point Progress: Gonorrhea Point of Care Tests.Expert review of molecular diagnostics · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Gonorrhoea treatment failure caused by aEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A Jeanine AbramsFrom the *CDC Division of STD Prevention, Atlanta, GA; †Oklahoma State Department of Health, HIV/STD Service, Oklahoma City, OK; and ‡Texas Department of State Health Services, Laboratory Services Section, Austin, TX.
Robert D Kirkcaldy
Kevin Pettus
Jan L Fox
Grace Kubin
David L Trees

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

We report a case of Neisseria gonorrhoeae with a non-mosaic penA allele that exhibited decreased susceptibility to extended-spectrum cephalosporins, including a ceftriaxone minimum inhibitory concentration of 0.5 μg/mL. An analysis of resistance determinants suggested that the observed phenotype might have resulted from the combined effects of mutations in multiple genes.

Indexed as

AdultAllelesAnti-Bacterial AgentsCarrier ProteinsCeftriaxoneDrug Resistance, BacterialGonorrheaHumansMaleMicrobial Sensitivity TestsMutationNeisseria gonorrhoeaePhenotypeSerine-Type D-Ala-D-Ala CarboxypeptidaseUrethraUrethritisAnti-Bacterial AgentsCarrier ProteinsCeftriaxonepenicillin-binding protein 2, Neisseria gonorrhoeaeSerine-Type D-Ala-D-Ala Carboxypeptidase

Identifiers

PMID28703729
PMCPMC6932624

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.