SynthesisHeart and vessels2017
Perioperative depression or anxiety and postoperative mortality in cardiac surgery: a systematic review and meta-analysis.
Synthesis in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 56 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Associations Between Perioperative Depression or Anxiety, Salivary Cortisol and α-amylase, and Administered Anesthesia Type in Knee Arthroscopy With Anterior Cruciate Ligament Reconstruction (ACLR): Prospective, Randomized Trial
Factors Associated With Perioperative Anxiety Among Patients Undergoing Coronary Angiography or Angioplasty: a Cross-sectional Study
Predictive Modelling of Clinically Significant Depressive Symptoms After Coronary Artery Bypass Graft Surgery
Who cites it
56 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The impact of compassion-based interventions on perioperative anxiety and depression: A systematic review and meta-analysis.Journal of affective disorders · 2024Pooled it
- Efficacy and safety of perioperative application of ketamine on postoperative depression: A meta-analysis of randomized controlled studies.Molecular psychiatry · 2023Pooled it
- Anxiety is associated with higher recurrence of atrial fibrillation after catheter ablation: A meta-analysis.Clinical cardiology · 2022Pooled it
- Music intervention to relieve anxiety and pain in adults undergoing cardiac surgery: a systematic review and meta-analysis.Open heart · 2021Pooled it
- Effects of an Informational Video About Anesthesia on Pre- and Post-Elective Cesarean Section Anxiety and Recovery: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2020Trial
- Low Preoperative Mental and Physical Health is Associated with Poorer Postoperative Recovery in Patients Undergoing Day Surgery: A Secondary Analysis from a Randomized Controlled Study.World journal of surgery · 2019Trial
- Frailty Assessment and Its Impact in Hospital Outcomes After Cardiac Surgery - A Prospective Observational Study.Brazilian journal of cardiovascular surgery · 2026Observational
- Impact of preoperative depression severity and antidepressant medication use on perioperative outcomes and long-term weight loss following primary bariatric surgery.Surgical endoscopy · 2026Article
- Type A and Type D Personality in Cardiovascular Health: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Unlocking patient insights: a prospective study on patient reported outcome measures in thoracic surgery.Journal of cardiothoracic surgery · 2026Observational
- Association Between Depression and Increased Odds of Inpatient Mortality Following Hip Fracture Repair.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- Mapping Global Trends and Research Hotspots in Postoperative Depression: A Bibliometric Analysis.Behavioural neurology · 2026Article
- Perioperative sleep management in cardiac surgery: an evidence-oriented narrative review of pharmacological, behavioral, and respiratory support strategies.Frontiers in cardiovascular medicine · 2026Review
- Patient-Centered Cardiac Surgery: Psychosocial Challenges, Evidence-Based Interventions, and Future Horizons.Healthcare (Basel, Switzerland) · 2025Review
- Language-specific approaches to reduce perioperative stress and anxiety related to anaesthesia for patients with limited English proficiency: A narrative review.Journal of perioperative practice · 2025Review
- Article
- Factors associated with perioperative anxiety among patients undergoing coronary angiography or angioplasty: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- From surgery to recovery: Measuring success through quality of life and functional improvements after cardiac surgery.World journal of cardiology · 2025Article
- Telemedicine/Telerehabilitation to Expand Enhanced Recovery After Surgery Interventions in Minimally Invasive Mitral Valve Surgery.Journal of clinical medicine · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We performed a systematic review and meta-analysis to determine whether perioperative depression and anxiety are associated with increased postoperative mortality in patients undergoing cardiac surgery. MEDLINE and EMBASE were searched through January 2017 using PubMed and OVID, to identify observational studies enrolling patients undergoing cardiac surgery and reporting relative risk estimates (RREs) (including odds, hazard, or mortality ratios) of short term (30 days or in-hospital) and/or late all-cause mortality for patients with versus without perioperative depression or anxiety. Study-specific estimates were combined using inverse variance-weighted averages of logarithmic RREs in the random-effects models. Our search identified 16 eligible studies. In total, the present meta-analysis included data on 236,595 patients undergoing cardiac surgery. Pooled analysis demonstrated that perioperative depression was significantly associated with increased both postoperative early (RRE, 1.44; 95% confidence interval [CI] 1.01-2.05; p = 0.05) and late mortality (RRE, 1.44; 95% CI 1.24-1.67; p < 0.0001), and that perioperative anxiety significantly correlated with increased postoperative late mortality (RRE, 1.81; 95% CI 1.20-2.72; p = 0.004). The relation between anxiety and early mortality was reported in only one study and not statistically significant. In the association of depression with late mortality, there was no evidence of significant publication bias and meta-regression indicated that the effects of depression are not modulated by the duration of follow-up. In conclusion, perioperative depression and anxiety may be associated with increased postoperative mortality in patients undergoing cardiac surgery.
Indexed as
Identifiers
28702898What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.