Evidence map›Paper›PMID 28702893›Full record

ArticleBreast cancer research and treatment2017

Medical costs of treating breast cancer among younger Medicaid beneficiaries by stage at diagnosis.

Justin G Trogdon, Donatus U Ekwueme, Diana Poehler, Cheryll C Thomas, Katherine Reeder-Hayes, Benjamin T Allaire

Open access · greenAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. AnFrontiers in pharmacology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Justin G TrogdonUniversity of North Carolina, 1101-B McGavran-Greenberg Bldg., 135 Dauer Dr., CB-7411, Chapel Hill, NC, 27599-7411, USA. justintrogdon@unc.edu.
Donatus U EkwuemeCenters for Disease Control and Prevention, Atlanta, GA, USA.
Diana PoehlerRTI International, Research Triangle Park, NC, USA.
Cheryll C ThomasCenters for Disease Control and Prevention, Atlanta, GA, USA.
Katherine Reeder-HayesUniversity of North Carolina, 1101-B McGavran-Greenberg Bldg., 135 Dauer Dr., CB-7411, Chapel Hill, NC, 27599-7411, USA.
Benjamin T AllaireRTI International, Research Triangle Park, NC, USA.
Centers for Disease Control and Prevention · USRTI International · USUniversity of North Carolina at Chapel Hill · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundYounger women (aged 18-44 years) diagnosed with breast cancer often face more aggressive tumors, higher treatment intensity, and lower survival rates than older women. In this study, we estimated incident breast cancer costs by stage at diagnosis and by race for younger women enrolled in Medicaid.

methodsWe analyzed cancer registry data linked to Medicaid claims in North Carolina from 2003 to 2008. We used Surveillance, Epidemiology, and End Results (SEER) Summary 2000 definitions for cancer stage. We split breast cancer patients into two cohorts: a younger and older group aged 18-44 and 45-64 years, respectively. We conducted a many-to-one match between patients with and without breast cancer using age, county, race, and Charlson Comorbidity Index. We calculated mean excess total cost of care between breast cancer and non-breast cancer patients.

resultsAt diagnosis, younger women had a higher proportion of regional cancers than older women (49 vs. 42%) and lower proportions of localized cancers (44 vs. 50%) and distant cancers (7 vs. 9%). The excess costs of breast cancer (all stages) for younger and older women at 6 months after diagnosis were $37,114 [95% confidence interval (CI) = $35,769-38,459] and $28,026 (95% CI = $27,223-28,829), respectively. In the 6 months after diagnosis, the estimated excess cost was significantly higher to treat localized and regional cancer among younger women than among older women. There were no statistically significant differences in excess costs of breast cancer by race, but differences in treatment modality were present among younger Medicaid beneficiaries.

conclusionsYounger breast cancer patients not only had a higher prevalence of late-stage cancer than older women, but also had higher within-stage excess costs.

Indexed as

Health Care CostsMedicaidAdolescentAdultAge FactorsAge of OnsetBreast NeoplasmsComorbidityFemaleHumansMiddle AgedMortalityNeoplasm StagingNorth CarolinaRegistriesSEER ProgramBreast cancerMedicaidMedical care costsYounger women

Identifiers

PMID28702893
PMCPMC6081748
OpenAlexW2735930686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.