Evidence map›Paper›PMID 28702844›Full record

ArticleWorld journal of urology2017

Influence of acetylsalicylic acid and low-molecular weight heparins on the formation of renal hematoma after shock wave lithotripsy.

Christoph Schregel, Hubert John, Marco Randazzo, Isabelle Keller

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02875717 (Influence of Acetylsalicylic Acid and Low Molecular Weight Heparins on the Incidence of Renal Hematoma of Shockwave Lithotripsy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02875717 completednot on this map

Influence of Acetylsalicylic Acid and Low Molecular Weight Heparins on the Incidence of Renal Hematoma of Shockwave Lithotripsy

TypeobservationalSponsorKantonsspital Winterthur KSWRan2009 to 2015Enrolled500ConditionsUrolithiasis, Renal HematomaArmsAcetylsalicylic acid, low molecular weight heparin
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Canadian Urological Association guideline: Management of ureteral calculi - Full-text.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christoph SchregelDepartment of Urology, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland. christophschregel@gmx.de.ORCID http://orcid.org/0000-0002-0127-9774
Hubert JohnDepartment of Urology, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Marco RandazzoDepartment of Urology, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Isabelle KellerDepartment of Urology, Kantonsspital Winterthur, Brauerstrasse 15, 8401, Winterthur, Switzerland.
Kantonsspital Winterthur · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the risk of renal hematoma (RHT) after shock wave lithotripsy (SWL) among patients on acetylsalicylic acid (ASA) or low-molecular-weight heparin (LMWH). PATIENTS AND

methodsRetrospective analysis of 434 patients treated with SWL for nephrolithiasis and ureterolithiasis of the proximal ureter. Primary endpoint was detection of RHT by ultrasound the day after SWL. Secondary outcome variables included transfusion of erythrocyte concentrate(s), interventions, hospital readmission or death due to RHT within 30 days of SWL. Binary logistic regression analysis was used including a post hoc one-way analysis.

resultsOf 434 patients, 33 (7.6%) and 67 (15.4%) patients were medicated with ASA and LMWH, respectively. RHT was detected in 20 of 434 (4.6%) patients. Of those, 3 (20%) were on ASA, 6 (35%) were on LMWH, 1 (5%) was on ASA and LMWH, and 10 (50%) had no anticoagulation. Univariate analysis showed a statistically significant higher risk for RHT among patients on ASA (p = 0.04) and LWMH (p = 0.02) with an untreated urinary tract infection (UTI) (p = 0.008) and history of cardiovascular disease (p = 0.028). On multivariate analysis, ASA medication, untreated UTI (OR 4.4, 95% CI 1.31-14.75, p = 0.016 and OR 5.79, 95% CI 1.65-20.32, p = 0.03) and a therapeutic dose of LMWH (OR 10.4, 95% CI 1.74-62.27, p = 0.01) were independent predictors for RHT.

conclusionsBefore SWL, a patient risk profile should be evaluated. If feasible, LMWH in therapeutic dosing should be avoided, and ASA should be discontinued. UTI should be treated before SWL in any case.

trial registrationhttp://www.clinicaltrials.gov ; Identifier NCT02875717.

Indexed as

HematomaKidneyAdultAspirinBlood CoagulationFemaleHematologic AgentsHeparin, Low-Molecular-WeightHumansKidney CalculiLithotripsyMaleMiddle AgedNephrolithiasisRetrospective StudiesRisk AssessmentAspirinHematologic AgentsHeparin, Low-Molecular-WeightAcetylsalicylic acidLow-molecular-weight heparinsRenal hematomaShock wave lithotripsyUrinary tract infection

Identifiers

PMID28702844
OpenAlexW2734592479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.