Evidence map›Paper›PMID 28702829›Full record

Trial reportSleep & breathing = Schlaf & Atmung2018

Severe obstructive sleep apnea treatment with oral appliance: the impact on obstructive, central and mixed events.

Maria de Lourdes Rabelo Guimarães, Ana Paula Hermont, Pedro Guimarães de Azevedo, Poliana Lima Bastos, Millena Teles Portela de Oliveira, Iracema Matos de Melo, Guilherme Salles Ottoboni, Gabriela Vedolin, Jorge Machado Caram

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Treatment options in obstructive sleep apnea.Internal and emergency medicine · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Maria de Lourdes Rabelo GuimarãesFaculty of Dentistry, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627-Pampulha, Belo Horizonte, MG, 31270-901, Brazil. mlourdesrg@gmail.com.
Ana Paula HermontFaculty of Dentistry, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627-Pampulha, Belo Horizonte, MG, 31270-901, Brazil.
Pedro Guimarães de AzevedoPontifícia Universidade Católica de Minas Gerais, Av: Dom José Gaspar, 500 Coração Eucaristíco, Belo Horizonte, MG, 30535-901, Brazil.
Poliana Lima BastosDepartment of Prosthesis and Occlusion, Universidade Federal do Ceará, Av. da Universidade, 2853-Benfica, Fortaleza, CE, 60020-181, Brazil.
Millena Teles Portela de OliveiraUniversidade Federal do Ceará, Av. da Universidade, 2853-Benfica, Fortaleza, CE, 60020-181, Brazil.
Iracema Matos de MeloDepartment of Physiology and Pharmacology, Universidade Federal do Ceará, Av. da Universidade, 2853-Benfica, Fortaleza, CE, 60020-181, Brazil.
Guilherme Salles OttoboniFaculdade de Odontologia de Piracicaba, Unicamp, Av. Limeira, 901-Bairro Areião, Piracicaba, SP, 13414-903, Brazil.
Gabriela VedolinPontificia Universidade Catolica do Rio Grande do Sul, Av. Ipiranga, 6681-Partenon, Porto Alegre, RS, 90619-900, Brazil.
Jorge Machado CaramFaculty of Dentistry, Universidade Federal de Minas Gerais, Av. Pres. Antônio Carlos, 6627-Pampulha, Belo Horizonte, MG, 31270-901, Brazil.
Universidade Federal de Minas Gerais · BRUniversidade Federal do Ceará · BRPontifícia Universidade Católica de Minas Gerais · BRPontifícia Universidade Católica do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to evaluate the effectiveness of two types of oral appliance (OA) in the treatment of severe obstructive sleep apnea syndrome (OSAS) and their impact on the reduction of obstructive, central and mixed apneas.

methodsForty-eight patients suffering from severe OSAS with a history of non-adherence to positive airway pressure therapy were treated with OA (lingual orthosis and combined orthosis). Polysomnography exams were performed before and after treatment. Computed tomography and cephalometric radiography were requested for all patients to evaluate the titrated position of the OA and the airspace obtained. Statistical tests used the Minitab, version 17, program. The level of statistical significance was 5%.

resultsBefore treatment, the mean AHI was 56.3 ± 19.1 events/h. It decreased to 8.1 ± 5.2 after the OA titration (p ≤ 0.001). There was a significant reduction in obstructive events from 43.0 ± 20.2 to 7.1 ± 4.6 events/h (p ≤ 0.001). The reduction in central events after OA treatment was also significant (from 5.1 ± 9.3 to 0.8 ± 1.9 events/h; p ≤ 0.001), whereas that in mixed events decreased from 6.4 ± 9.5 to 0.1 ± 0.3 events/h (p ≤ 0.001). The minimum oxygen saturation also showed significant improvement after treatment (p ≤ 0.001). There was no statistically significant difference between both OA with respect to central events (p = 0.22) or mixed events (p = 0.98).

conclusionThe treatment was effective in reducing obstructive events which were evaluated through the AHI and minimum oxygen saturation. The oral appliances also normalized central and mixed events among patients with severe OSAS.

Indexed as

AdultAgedAged, 80 and overBrazilCephalometryHumansMaleMandibular AdvancementMiddle AgedPolysomnographySleep Apnea, ObstructiveYoung AdultObstructive sleep apneaOral appliancesOrthotic devicesSleep disordered breathing

Identifiers

PMID28702829
OpenAlexW2735464783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.