Evidence map›Paper›PMID 28702751›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2017

Complexes of gastrin with In

Marie Laval, Kathryn M Marshall, John Sachinidis, Andrew Scott, Mal Eutick, Graham S Baldwin

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marie LavalDepartment of Surgery, Austin Health, University of Melbourne, Level 8, Lance Townsend Building, Studley Road, Melbourne, VIC, 3084, Australia. mlaval@unimelb.edu.au.
Kathryn M MarshallDepartment of Surgery, Austin Health, University of Melbourne, Level 8, Lance Townsend Building, Studley Road, Melbourne, VIC, 3084, Australia.
John SachinidisDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia.
Andrew ScottDepartment of Molecular Imaging and Therapy, Austin Health, Melbourne, VIC, Australia.
Mal EutickPhebra Pty. Ltd, Hunters Hill, NSW, Australia.
Graham S BaldwinDepartment of Surgery, Austin Health, University of Melbourne, Level 8, Lance Townsend Building, Studley Road, Melbourne, VIC, 3084, Australia.
Austin Health · AUPYC Therapeutics (Australia) · AUUniversity of Melbourne · AU

Funding

National Health and Medical Research Council 1020983
6 · The paper itself

Abstract

The peptide hormone gastrin (Gamide) binds trivalent metal ions, including indium (In), ruthenium (Ru) and gallium (Ga), with high affinity. Complexes of gastrin with chelated isotopes of In and Ga have previously been used for the location of tumours expressing the cholecystokinin 2 receptor (CCK2R). The aim of the present study was to purify the complexes of Gamide with radioactive isotopes of In, Ru or Ga and to investigate their ability to bind to the CCK2R. The radioactive Gamide complexes were purified on Sep-Pak C18 cartridges or by anion exchange HPLC. Binding to the CCK2R was assessed with a stably transfected clone of the gastric carcinoma cell line AGS. The

Indexed as

Cell LineCoordination ComplexesGalliumGallium RadioisotopesGastrinsHumansIndiumProtein BindingReceptor, Cholecystokinin BRutheniumRuthenium RadioisotopesCoordination ComplexesGalliumGallium RadioisotopesGastrinsIndiumReceptor, Cholecystokinin BRutheniumRuthenium RadioisotopesGalliumGastrinIndiumIronRuthenium

Identifiers

PMID28702751
OpenAlexW2734511201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.