Evidence map›Paper›PMID 28702741›Full record

Trial reportObesity surgery2018

Massive Weight Loss Obtained by Bariatric Surgery Affects Semen Quality in Morbid Male Obesity: a Preliminary Prospective Double-Armed Study.

Jinous Samavat, Giulia Cantini, Francesco Lotti, Alessandra Di Franco, Lara Tamburrino, Selene Degl'Innocenti, Elisa Maseroli, Erminio Filimberti, Enrico Facchiano, Marcello Lucchese and 5 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 9 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 9 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Effect of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Male Sexual Function: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  3. Australasian recurrent pregnancy loss clinical management guideline 2024, part II.The Australian & New Zealand journal of obstetrics & gynaecology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Jinous SamavatEndocrinology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Giulia CantiniEndocrinology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Francesco LottiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Alessandra Di FrancoEndocrinology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Lara TamburrinoSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Selene Degl'InnocentiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Elisa MaseroliSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Erminio FilimbertiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Enrico FacchianoDepartment of Surgery, Bariatric and Metabolic Surgery Unit, Santa Maria Nuova Hospital, Piazza Santa Maria Nuova, 50122, Florence, Italy.
Marcello LuccheseDepartment of Surgery, Bariatric and Metabolic Surgery Unit, Santa Maria Nuova Hospital, Piazza Santa Maria Nuova, 50122, Florence, Italy.
Monica MuratoriSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Gianni FortiEndocrinology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Elisabetta BaldiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Mario MaggiSexual Medicine and Andrology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy.
Michaela LuconiEndocrinology Unit, Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, viale Pieraccini 6, 50139, Florence, Italy. michaela.luconi@unifi.it.ORCID http://orcid.org/0000-0001-5186-064X
University of Florence · ITSanta Maria Nuova Hospital · IT

Funding

Ente Cassa di Risparmio di Firenze (IT) 2014/0764;2013/0326Italian Ministry of University and Research 2010C8ERKXItalian Ministry of University and Research RBSI14LFMQ
6 · The paper itself

Abstract

objectivesThe aim of this study is to evaluate the effect of massive weight loss on the seminal parameters at 6 months from bariatric surgery.

designTwo-armed prospective study performed in 31 morbidly obese men, undergoing laparoscopic roux-en-Y-gastric bypass (n = 23) or non-operated (n = 8), assessing sex hormones, conventional (sperm motility, morphology, number, semen volume), and non-conventional (DNA fragmentation and seminal interleukin-8), semen parameters, at baseline and after 6 months from surgery or patients' recruitment.

resultsIn operated patients only, a statistically significant improvement in the sex hormones was confirmed. Similarly, a positive trend in the progressive/total sperm motility and number was observed, though only the increase in semen volume and viability was statistically significant (Δ = 0.6 ml and 10%, P < 0.05, respectively). A decrease in the seminal interleukin-8 levels and in the sperm DNA fragmentation was also present after bariatric surgery, whereas these parameters even increased in non-operated subjects. Age-adjusted multivariate analysis showed that the BMI variations significantly correlated with the changes in the sperm morphology (β = -0.675, P = 0.025), sperm number (β = 0.891, P = 0.000), and semen volume (r = 0.618, P = 0.015).

conclusionThe massive weight loss obtained with bariatric surgery was associated with an improvement in some semen parameters. The correlations found between weight loss and semen parameter variations after surgery suggest that these might occur early downstream of the testis and more slowly than the changes in the sex hormones.

Indexed as

Bariatric SurgerySemen AnalysisAdultBody Mass IndexFollow-Up StudiesHumansInfertility, MaleInterleukin-8LaparoscopyLongitudinal StudiesMaleMiddle AgedObesity, MorbidPilot ProjectsSemenTreatment OutcomeCXCL8 protein, humanInterleukin-8Body mass indexHypogonadismLongitudinal studyMale infertilitySemen analysisWeight loss

Identifiers

PMID28702741
OpenAlexW2734850796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.