ArticleJournal of pregnancy and child health2017
Prenatal Depression Risk Factors, Developmental Effects and Interventions: A Review.
Article in Journal of pregnancy and child health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
88 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- The evidence base of interventions to treat antenatal depression: a meta-analysis of randomized controlled trials.Archives of women's mental health · 2026Pooled it
- Effect of technology-supported mindfulness-based interventions for maternal depression: a systematic review and meta-analysis with implementation perspectives for resource-limited settings.BMC pregnancy and childbirth · 2025Pooled it
- The association between body image and depressive symptoms in pregnant and postpartum women: a meta-analysis.Frontiers in public health · 2025Pooled it
- Perinatal depression and associated factors in Ethiopia: a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Epigenome-wide association studies of prenatal maternal mental health and infant epigenetic profiles: a systematic review.Translational psychiatry · 2023Pooled it
- Pooled it
- Psycho-educational interventions focused on maternal or infant sleep for pregnant women to prevent the onset of antenatal and postnatal depression: A systematic review.Neuropsychopharmacology reports · 2021Pooled it
- Repetitive transcranial magnetic stimulation treatment for peripartum depression: systematic review & meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- The Perinatal Mental Health of Indigenous Women: A Systematic Review and Meta-Analysis.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2020Pooled it
- Language-Related Differences in Prenatal Depression Screening Uptake in the USA Midwest, 2019-2024.BJPsych open · 2026Article
- Association between maternal and neonatal outcomes and psychosocial risk levels in pregnant women: a convergent parallel mixed methods study protocol.Reproductive health · 2026Article
- Factors related to prenatal depression among hospitalized high-risk pregnant women in South Korea: a cross-sectional study focused on resilience, pregnancy stress, and marital satisfaction.Child health nursing research · 2026Article
- Sex differences in the risk of autistic-related traits in toddlers born to mothers with perinatal depression: Evidence from human cohort and mouse study.Molecular psychiatry · 2026Article
- Fetal attachment and infant temperament: The mediating role of perinatal mental health.Journal of affective disorders · 2026Article
- The magnitude and population burden of educational inequalities in adverse birth outcomes.Scientific reports · 2026Article
- Associations Between Adverse Childhood Experiences and Prenatal Depression Mediated Through Family Communication in Chinese Pregnant Women: Causal Mediation Analysis.Depression and anxiety · 2026Article
- Association between depression during pregnancy and preterm birth: Results from population cohorts and mouse experimental models.PloS one · 2026Article
- Sleep and fatigue complaints during pregnancy versus perinatal depression: Impact on toddler cognition.Journal of affective disorders · 2026Article
- Prevalence and Factors Associated With Depression Among Antenatal and Postnatal Women Attending Government Health Clinics in Selangor, Malaysia: Protocol for a Cross-Sectional Study.JMIR research protocols · 2025Article
- Association of prenatal alcohol exposure and prenatal depressive symptoms with offspring hair cortisol in childhood and adolescence.BMC psychiatry · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This narrative review based on a literature search in PubMed and PsycInfo on the two terms prenatal and antenatal depression includes empirical studies, reviews and meta-analyses that have been published during the last 5 years on risk factors, developmental effects and interventions for prenatal depression. Risk factor studies that met criteria feature demographic measures (lower socioeconomic status, less education, non-marital status, non-employment, less social support and health locus of control, unintended pregnancy, partner violence and history of child abuse) and physiological variables (cortisol, amylase, and pro-inflammatory cytokines and intrauterine artery resistance). The negative effects include postpartum depression, paternal depression, and prematurity and low birth weight. Negative effects on infants include greater right frontal EEG, amygdala connectivity, cortical thinning and more difficult temperament. In childhood, externalizing and internalizing problems have been reported. The data on prenatal antidepressants (specifically SSRIs) reveal negative effects including internalizing problems as well as a greater risk for autism spectrum disorder. Prenatal interventions that have been effective include interpersonal psychotherapy, peer support, massage therapy, yoga, tai chi, and aerobic exercise. Potential underlying mechanisms are discussed as well as methodological limitations including homogeneity of samples and lack of randomization to intervention groups. Despite these limitations, the literature highlights the need for prenatal depression screening and intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.