Evidence map›Paper›PMID 28702491›Full record

ArticleData in brief2017

Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome.

Konstantin Gunbin, Leonid Peshkin, Konstantin Popadin, Sofia Annis, Rebecca R Ackermann, Konstantin Khrapko

Abstract read
In one paragraph

Article in Data in brief, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Konstantin GunbinInstitute of Cytology and Genetics SB RAS and Novosibirsk State University, Russia.
Leonid PeshkinHarvard Medical School, Boston, USA.
Konstantin PopadinUniversity of Lausanne, Center for Integrative Genomics, Switzerland.
Sofia AnnisNortheastern University, Boston, USA.
Rebecca R AckermannDepartment of Archaeology & Human Evolution Research Institute, University of Cape Town, South Africa.
Konstantin KhrapkoNortheastern University, Boston, USA.

Funding

Systems Analysis of cell type differentiation in Xenopus developmentR01HD073104 · NICHD · HARVARD MEDICAL SCHOOL · PI KIRSCHNER, MARC WALLACE, PESHKIN, LEON · 2012 to 2022
$6.7M
Proteomics of Cell Signaling in Embryogenesis.R01HD091846 · NICHD · HARVARD MEDICAL SCHOOL · PI GYGI, STEVEN P, KIRSCHNER, MARC WALLACE · 2017 to 2021
$3.1M
NICHD NIH HHS R01 HD073104NICHD NIH HHS R01 HD091846
6 · The paper itself

Abstract

The data and methods presented in this article are supplementing the research article "Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis", DOI: 10.1016/j.mito.2016.12.001 (Gunbin et al., 2017) [1]. Mitochondrial DNA is known to get inserted into nuclear DNA to form NUMTs, i.e. nuclear DNA pseudogenes of the mtDNA. We present here the sequences of selected NUMTs, in which time of integration can be determined with sufficient precision. We report their chromosomal positions , their position within the great ape mtDNA phylogeny, and their times of integration into the nuclear genome. The methods used to generate the data and to control their quality are also presented. The dataset is made publicly available to enable critical or extended analyzes.

Indexed as

Human evolutionMitochondrial DNANUMTPseudogenePunctuated evolutionSpeciation

Identifiers

PMID28702491
PMCPMC5491396

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.