ReviewPneumonia (Nathan Qld.)2016
Prevalence, pathogenesis, therapy, and prevention of cardiovascular events in patients with community-acquired pneumonia.
Review in Pneumonia (Nathan Qld.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- ASPirin for Acute Pneumonia in the elderlY (ASPAPY): protocol of a multicentre randomised double-blind placebo-controlled trial.BMJ open · 2025Article
- Retrospective Analysis of Predictive Biomarkers of Survival in Acute Exacerbation of Fibrosing Interstitial Lung Disease: A Single-Center Study in Spain.Journal of clinical medicine · 2025Article
- A nomogram for predicting mortality risk in geriatric patients with hip fractures complicated by pneumonia: A multicenter study.SAGE open medicine · 2025Article
- Association betweenBiomedical reports · 2024Review
- Bacterial Pneumonia and Stroke Risk: A Nationwide Longitudinal Followup Study.Current neurovascular research · 2024Article
- Acute Myocardial Infarction-Related Hospitalizations in Non-elderly Patients with Pneumonia: a Population-Based Study.SN comprehensive clinical medicine · 2023Article
- Thromboembolic Risk in Patients With Pneumonia and New-Onset Atrial Fibrillation Not Receiving Anticoagulation Therapy.JAMA network open · 2022Article
- Acute Lower Respiratory Tract Infection Increased the Risk of Cardiovascular Events and All-Cause Mortality in Elderly Patients With Stable Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Article
- Host- and Pathogen-Related Factors for Acute Cardiac Events in Pneumococcal Pneumonia.Open forum infectious diseases · 2020Article
- Ventilator for the management of patients with severe pneumonia: A protocol of systematic review.Medicine · 2020Article
- Cardiovascular Events After Community-Acquired Pneumonia: A Global Perspective with Systematic Review and Meta-Analysis of Observational Studies.Journal of clinical medicine · 2020Review
- Cardiac complications in community-acquired pneumonia and COVID-19.African journal of thoracic and critical care medicine · 2020Review
- Post-Infectious Myocardial Infarction: New Insights for Improved Screening.Journal of clinical medicine · 2019Article
- Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia.International journal of molecular sciences · 2018Review
- Triptych of the Hermit Saints: pneumococcal polysaccharide vaccines for the elderly.Risk management and healthcare policy · 2018Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is now well recognised that cardiac events occur relatively commonly in patients with acute community-acquired pneumonia. While these events are more frequent in patients with underlying risk factors-such as those with underlying chronic cardiovascular and respiratory comorbidities, the elderly, and in nursing home residents-they also occur in patients with no underlying risks other than severe pneumonia. Recent research elucidating the underlying pathogenic mechanisms related to these cardiac events has indicated a probable role for platelet activation, which is possibly exacerbated by pneumolysin in the case of pneumococcal infections. This, in turn, has resulted in the identification of possible therapeutic strategies targeting platelet activation, as well as the cardio-toxic activity of pneumolysin. These issues represent the primary focus of the current review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.