Evidence map›Paper›PMID 28702285›Full record

ArticlePneumonia (Nathan Qld.)2016

Comparison between diagnosis and treatment of community-acquired pneumonia in children in various medical centres across Europe with the United States, United Kingdom and the World Health Organization guidelines.

Vytautas Usonis, Rimvydas Ivaskevicius, Javier Diez-Domingo, Susanna Esposito, Oana G Falup-Pecurariu, Adam Finn, Fernanda Rodrigues, Vana Spoulou, George A Syrogiannopoulos, David Greenberg and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pneumonia (Nathan Qld.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
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  4. Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 8 countries.

Vytautas UsonisClinic of Children's Diseases, Vilnius University, Vilnius, Lithuania.
Rimvydas IvaskeviciusClinic of Children's Diseases, Vilnius University, Vilnius, Lithuania.
Javier Diez-DomingoFISABIO-Public Health, (CSISP), Valencia, Spain.
Susanna EspositoDepartment of Maternal and Paediatric Sciences, Università degli Studi di Milano Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Oana G Falup-PecurariuUniversity Children's Hospital, Transylvania University, Brasov, Romania.
Adam FinnBristol Children's Vaccine Centre, School of Clinical Sciences, University of Bristol, Bristol, UK.
Fernanda RodriguesInfectious Diseases Unit & Emergency Service, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Vana SpoulouFirst Department of Paediatrics, Agia Sophia Children's Hospital, Athens, Greece.
George A SyrogiannopoulosDepartment of Paediatrics, General University Hospital of Larissa, Larissa, Greece.
David GreenbergThe Paediatric Infectious Disease Unit, Soroka University Medical Center, Beer-Sheva, Israel.
CAP-PRI Working Group
Vilnius University · LTBen-Gurion University of the Negev · ILHospitais da Universidade de Coimbra · PTUniversity of Milan · ITTransylvania University of Brașov · ROUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to review the current status and usage of guidelines in the diagnosis and treatment of community-acquired pneumonia (CAP) in European countries and to compare to established guidelines in the United States (US), United Kingdom (UK), and the World Health Organization (WHO).

methodsA questionnaire was developed and distributed by the Community-Acquired Pneumonia Paediatric Research Initiative (CAP-PRI) working group and distributed to medical centres across Europe.

resultsOut of 19 European centres, 6 (31.6 %) used WHO guidelines (3 in combination with other guidelines), 5 (26.3 %) used national guidelines, and 5 (26.3 %) used local guidelines. Chest radiograph and complete blood count were the most common diagnostic examinations, while evaluation of clinical symptoms and laboratory tests varied significantly. Tachypnoea and chest recession were considered criteria for diagnosis in all three guidelines. In US and UK guidelines blood cultures, atypical bacterial and viral detection tests were recommended. In European centres in outpatient settings, amoxicillin was used in 16 (84 %) centers, clarithromycin in 9 (37 %) centers and azithromycin in 7 (47 %) centers, whereas in hospital settings antibiotic treatment varied widely. Amoxicillin is recommended as the first drug of choice for outpatient treatment in all guidelines.

conclusionsAlthough local variations in clinical criteria, laboratory tests, and antibiotic resistance rates may necessitate some differences in standard empirical antibiotic regimens, there is considerable scope for standardisation across European centres for the diagnosis and treatment of CAP.

Indexed as

Antibacterial treatmentCommunity-acquired pneumoniaCommunity-acquired pneumonia diagnosisCommunity-acquired pneumonia treatmentGuidelines

Identifiers

PMID28702285
PMCPMC5469201
OpenAlexW2322418816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.