Evidence map›Paper›PMID 28702225›Full record

ArticleClinical diabetes and endocrinology2015

The association of dyslipidemia and obesity with glycated hemoglobin.

Jayesh Sheth, Ankna Shah, Frenny Sheth, Sunil Trivedi, Nutan Nabar, Navneet Shah, Premal Thakor, Rama Vaidya

Open access · goldAbstract read
In one paragraph

Article in Clinical diabetes and endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Lipidomic profiling of endometrial cancer using desorption electrospray ionization mass spectrometry imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  11. Exosomal microRNAs in diabetic heart disease.Cardiovascular diabetology · 2022
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  19. Review
  20. Lipid metabolism and carcinogenesis, cancer development.American journal of cancer research · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jayesh ShethDepartment of Biochemistry and Molecular Genetics, FRIGE's Institute of Human Genetics, FRIGE House,, Jodhpur Gam Road, Satellite, Ahmedabad, 380015 India.
Ankna ShahDepartment of Biochemistry and Molecular Genetics, FRIGE's Institute of Human Genetics, FRIGE House,, Jodhpur Gam Road, Satellite, Ahmedabad, 380015 India.
Frenny ShethDepartment of Biochemistry and Molecular Genetics, FRIGE's Institute of Human Genetics, FRIGE House,, Jodhpur Gam Road, Satellite, Ahmedabad, 380015 India.
Sunil TrivediDepartment of Biochemistry and Molecular Genetics, FRIGE's Institute of Human Genetics, FRIGE House,, Jodhpur Gam Road, Satellite, Ahmedabad, 380015 India.
Nutan NabarUnit of Endocrine and Metabolic Disorders, Kasturba Health Society, Medical Research Centre, Mumbai, 400056 India.
Navneet ShahDepartment of Diabetes and Endocrinology, Sterling Hospital, Ahmedabad, 380052 India.
Premal ThakorGujarat Diabetic Association, Ahmedabad, 380007 India.
Rama VaidyaUnit of Endocrine and Metabolic Disorders, Kasturba Health Society, Medical Research Centre, Mumbai, 400056 India.
Centre For Human Genetics · INKasturba Hospital · INSterling Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDyslipidemia and obesity are the most common complex metabolic disorders taking the highest toll of health resources globally by its increasing incidences. This consequently leads to type 2 diabetes mellitus (T2DM) and cardiovascular disorders (CVDs) with variable reports about the role of metabolic factors on glycemic control. The current study is designed to determine the association of dyslipidemia and obesity with glycated hemoglobin (HbA1c) in T2DM and non-diabetic subjects.

methodsThe present study was carried out in 931 subjects from urban Western India including 430 diabetic and 501 non-diabetic subjects with detailed anthropometric parameters. All subjects were investigated for HbA1c and lipid parameters like TC, TG, HDL-C, LDL-C and non-HDL-C.

resultsDyslipidemia, central- and peripheral- obesity were observed (50.27 %; 75 % and 59.83 %) in all the study subjects respectively. Additionally, hyper-non-HDL-C was detected in 23.49 % and 22.56 % in T2DM and non-diabetic subjects. Significant linear associations of hyper-TC, hyper-LDL-C and hyper-non-HDL-C were observed with HbA1c in T2DM and non-diabetic control subjects respectively. Centrally- and peripherally- obese dyslipidemic subjects also showed a significant association with HbA1c in T2DM and control subjects respectively.

conclusionThis study demonstrates the high prevalence of dyslipidemia and obesity in all subjects irrespective of their disease status in a Western Indian population. The dyslipidemic obese subjects had significant linear association with HbA1c in T2DM subjects.

Indexed as

DyslipidemiaHbA1cnon-HDL-CObesityT2DM

Identifiers

PMID28702225
PMCPMC5469195
OpenAlexW2136025336

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.