Evidence map›Paper›PMID 28702223›Full record

ArticleClinical diabetes and endocrinology2015

The potential role of incretin therapy in the hospital setting.

Jennifer J Macdonald, Shristi Neupane, Roma Y Gianchandani

Open access · goldAbstract read
In one paragraph

Article in Clinical diabetes and endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennifer J MacdonaldDivision of Internal Medicine, University of Michigan Medical Center, 1500 E. Medical Center Drive, 3116Q Taubman Center, SPC 5368, Ann Arbor, MI 48109 USA.
Shristi NeupaneDivision of Metabolism, Endocrinology & Diabetes, University of Michigan Medical Center, Domino's Farms, Lobby G, Suite 1500, 24 Frank Lloyd Wright Drive, P.O. Box 482, Ann Arbor, MI 48106-0482 USA.
Roma Y GianchandaniDivision of Metabolism, Endocrinology & Diabetes, University of Michigan Medical Center, Domino's Farms, Lobby G, Suite 1500, 24 Frank Lloyd Wright Drive, P.O. Box 482, Ann Arbor, MI 48106-0482 USA.
University of Michigan–Ann Arbor · USAnn Arbor VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperglycemia has been associated with increased morbidity and mortality in hospitalized patients. Insulin has traditionally been the drug of choice for managing hyperglycemia in this setting, but carries a significant risk of hypoglycemia. Incretin-based therapies, including glucagon-like peptide-1, glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors, have potential use in the hospital. These agents have a relatively low risk of hypoglycemia, favorable short-term side effect profile, and can be used alone or in combination with insulin. Several small studies have supported the safety and efficacy of incretin therapies in the inpatient setting with the majority of data coming from the intensive care setting. Large-scale clinical studies are needed to further evaluate the potential role of incretins in the management of inpatient hyperglycemia.

Indexed as

Dipeptidyl peptidase-4 inhibitorGlucagon-like peptide-1 receptor agonistHyperglycemiaIncretinInpatient

Identifiers

PMID28702223
PMCPMC5469200
OpenAlexW2115620903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.