Evidence map›Paper›PMID 28702213›Full record

ArticleObesity science & practice2017

Monitoring the efficacy of omega-3 supplementation on liver steatosis and carotid intima-media thickness: a pilot study.

M-C Lacasse, A Tang, J Dubois, F Alvarez, S Spahis, M Chagnon, S Deschênes, E Levy

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

M-C LacasseDepartment of Radiology Centre Hospitalier de l'Université de Montréal (CHUM) Montréa Québec Canada.
A TangDepartment of Radiology Centre Hospitalier de l'Université de Montréal (CHUM) Montréa Québec Canada.
J DuboisDepartment of Radiology Centre Hospitalier Universitaire Ste-Justine Montréal Québec Canada.
F AlvarezCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine Montréal Québec Canada.
S SpahisCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine Montréal Québec Canada.
M ChagnonDepartment of Mathematics and Statistics, Pavillon André-Aisenstadt Université de Montréal Montréal Québec Canada.
S DeschênesDepartment of Radiology Centre Hospitalier Universitaire Ste-Justine Montréal Québec Canada.
E LevyCentre de Recherche du Centre Hospitalier Universitaire Ste-Justine Montréal Québec Canada.
Centre Hospitalier Universitaire Sainte-Justine · CACentre Hospitalier de l’Université de Montréal · CAUniversité de Montréal · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the effects of omega-3 supplementation on liver fat and carotid intima-media thickness (IMT) and to assess accuracy of ultrasound (US) for grading liver steatosis. MATERIALS AND

methodsIn this one-way crossover pilot study, we assigned children with obesity and liver steatosis to receive 1.2 g daily of omega-3 supplementation vs. inactive sunflower oil for 24 or 12 weeks. Liver fat content was assessed by magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI) and US, and common carotid IMT by US. Statistical analysis included Chi-square, Student's

resultsOmega-3 supplementation was associated with a trend towards decrease in MRS-determined liver fat fraction (0.7% and 2.1% decrease in the 24-week and 12-week omega-3 group, respectively) compared with the sunflower oil group (1.0% increase). These changes were not significant, whether assessed by MRS (

conclusionOmega-3 supplementation had no significant effect on liver fat fraction, but led to carotid IMT decrease in children with obesity and liver steatosis.

Indexed as

Carotid intima–media thickness (IMT)liver steatosisMRI‐proton density fat fraction (PDFF)omega‐3 fatty acids

Identifiers

PMID28702213
PMCPMC5478813
OpenAlexW2556788629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.