ReviewGastroenterology and hepatology from bed to bench2017
New insights in IBS-like disorders: Pandora's box has been opened; a review.
Review in Gastroenterology and hepatology from bed to bench, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05100719 (The Role of Irritable Bowel Syndrome in Lactose Intolerance), which is not on this map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION Trial): Protocol of a Multicentre Randomized Controlled Clinical Trial
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Assessing the Impact of the Low-FODMAP Diet on IBS Management in Asian Countries: A Systematic Review and Meta-Analysis of Evidence.Digestive diseases and sciences · 2025Pooled it
- Global research progress of visceral hypersensitivity and irritable bowel syndrome: bibliometrics and visualized analysis.Frontiers in pharmacology · 2023Pooled it
- European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus.United European gastroenterology journal · 2022Guideline
- Lactose intolerance but not lactose maldigestion is more frequent in patients with irritable bowel syndrome than in healthy controls: A meta-analysis.Neurogastroenterology and motility · 2019Pooled it
- Non-invasive measurement of accelerated gastrointestinal transit in pediatric patients using Contrast-enhanced Multispectral optoacoustic tomography.Npj imaging · 2026Article
- Effectiveness of a FODMAP-Based, Coach-Supervised, and Peer-Supported Lifestyle Program in Reducing Gastrointestinal and Extraintestinal Symptoms in Irritable Bowel Syndrome.Gastro hep advances · 2026Article
- Gallic acid alleviates visceral hyperalgesia following maternal separation in mice by inhibiting EphrinB2/EphB2 signaling mediated activation of neurons and glial cells.Frontiers in immunology · 2025Article
- Role of Anti-Vinculin Quantitative ELISA Test in Diagnosing Irritable Bowel Syndrome and Inflammatory Bowel Disease.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- Gluten-Free Diet for Fashion or Necessity? Review with New Speculations on Irritable Bowel Syndrome-like Disorders.Nutrients · 2024Review
- Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome.World journal of gastroenterology · 2024Article
- Deciphering the spatiotemporal transcriptional landscape of intestinal diseases (Review).Molecular medicine reports · 2024Review
- Role of Calprotectin, IL-6, and CRP in Distinguishing Between Inflammatory Bowel Disease and Diarrhea Predominant Irritable Bowel Syndrome.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2024Article
- Article
- Review
- New Insights and Evidence on "Food Intolerances": Non-Celiac Gluten Sensitivity and Nickel Allergic Contact Mucositis.Nutrients · 2023Article
- [Dermatitis herpetiformis and other forms of wheat sensitivity].Dermatologie (Heidelberg, Germany) · 2022Review
- Histamine: A Mediator of Intestinal Disorders-A Review.Metabolites · 2022Review
- Article
- Histamine Intolerance Originates in the Gut.Nutrients · 2021Review
- Dietary Patterns in Runners with Gastrointestinal Disorders.Nutrients · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most complained gastrointestinal symptoms are chronic diarrhea, bloating and abdominal pain. Once malignancies and inflammatory bowel diseases are excluded, irritable bowel syndrome (IBS) and the so called "IBS-like disorders" should be taken into account. The relationship between IBS as defined by Rome IV criteria and these clinical conditions is sometimes obscure, since many IBS patients identify food as a possible trigger for their symptoms. Here, we discuss IBS and the most common IBS-like disorders (celiac disease, non-celiac gluten sensitivity, fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs), lactose intolerance, small intestinal bacterial overgrowth (SIBO), α-amylase/trypsin inhibitor (ATIs), nickel allergic contact mucositis), focusing on epidemiologic, clinical, diagnostic and therapeutic aspects. Given the lack of specificity of symptoms, clinical investigation will be facilitated by awareness of these disorders as well as new specific diagnostic tools.
Indexed as
Identifiers
28702130PMC5495893What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.