Evidence map›Paper›PMID 28702020›Full record

ArticleFrontiers in microbiology2017

Repetitive Short-Term Stimuli Imposed in Poor Mixing Zones Induce Long-Term Adaptation of

Alexander Nieß, Michael Löffler, Joana D Simen, Ralf Takors

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Toward Engineering Biosystems With Emergent Collective Functions.Frontiers in bioengineering and biotechnology · 2020
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander NießInstitute of Biochemical Engineering, University of StuttgartStuttgart, Germany.
Michael LöfflerInstitute of Biochemical Engineering, University of StuttgartStuttgart, Germany.
Joana D SimenInstitute of Biochemical Engineering, University of StuttgartStuttgart, Germany.
Ralf TakorsInstitute of Biochemical Engineering, University of StuttgartStuttgart, Germany.
University of Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapidly changing concentrations of substrates frequently occur during large-scale microbial cultivations. These changing conditions, caused by large mixing times, result in a heterogeneous population distribution. Here, we present a powerful and efficient modeling approach to predict the influence of varying substrate levels on the transcriptional and translational response of the cell. This approach consists of two parts, a single-cell model to describe transcription and translation for an exemplary operon (

Indexed as

adaptation timesEscherichia colihybrid modelingpopulation heterogeneityscale-down

Identifiers

PMID28702020
PMCPMC5487534
OpenAlexW2731938260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.