ReviewFrontiers in endocrinology2017
Thyroid Autoimmunity and Lichen.
Review in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The risk of thyroid diseases in lichen sclerosus patients: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Lichen sclerosus. Part 1. Guideline of the DGG, DGGG, OEGGG and SGGG (S3-Level, AWMF Registry No. 013-105, July 2025.Geburtshilfe und Frauenheilkunde · 2026Article
- Systemic Disease Associations of Oral Lichenoid Disease: A Retrospective Case-Control Study.Oral diseases · 2026Article
- Thyroid dysfunction and its association with micronutrients, lipids, and inflammation: an analytical case-control study.BMC endocrine disorders · 2026Observational
- Integrating genomic structural equation modeling and experimental validation to unravel the genetic basis of male genital lichen sclerosus.Frontiers in immunology · 2026Article
- Article
- Multiple-Site Lichen Planus: An Italian Case Series of 44 Patients.Journal of clinical medicine · 2025Article
- Article
- Association Between Autoimmune Thyroid disease and Oral Lichen Planus: A Multi-Omic Genetic Analysis.International dental journal · 2025Article
- History of Breast Cancer in Patients with Oral Lichen Planus: A Case-Control Study.Journal of clinical medicine · 2024Article
- Possible Role of NRF2 in Cell Response to OZOILE (Stable Ozonides) in Children Affected by Lichen Sclerosus of Foreskin.Current issues in molecular biology · 2024Article
- The Potential Coexistence of Autoimmune Thyroid Diseases and Pediatric VulvarChildren (Basel, Switzerland) · 2024Article
- Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies.Biomedicines · 2023Review
- Lichen Sclerosus: A Current Landscape of Autoimmune and Genetic Interplay.Diagnostics (Basel, Switzerland) · 2022Review
- Thyroid disorders associated with lichen sclerosus: a case-control study in the All of Us Research Program.The British journal of dermatology · 2022Article
- Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus.Dentistry journal · 2022Article
- Association of Hashimoto's thyroiditis and anti-thyroid antibodies with oral lichen planus: A cross-sectional study.Frontiers in immunology · 2022Article
- Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto's Thyroiditis.Mediators of inflammation · 2020Review
- Oral lichen planus and thyroid gland diseases: possible associations.BMC oral health · 2019Article
- Lichen Sclerosus: An autoimmunopathogenic and genomic enigma with emerging genetic and immune targets.International journal of biological sciences · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lichen planus (LP) and lichen sclerosus (LS) are cutaneous-mucous diseases with uncertain epidemiology. Current data, which are likely to be underestimated, suggest a prevalence in the general population of 0.1-4% for cutaneous LP, 1.27-2.0% for oral LP, and 0.1-3.3% for LS. While etiology of lichen is still unknown, clinical and histological evidence show an (auto)immune pathogenesis. Association of lichen with autoimmune thyroid disease (AITD) has been investigated in few studies. This association appears better defined in the case of LS, while is more controversial for LP. In both situations, the frequency of the association is higher in females. We review the available literature on the correlation between the different types of lichen and AITD, and the literature on the genetic risk factors which are shared by both conditions. Such data suggest that a common pathogenic mechanism could be the cause for co-occurrence of lichen and AITD, at least in some patients. Additionally, analyzing literature data and in continuity with our previous work on other autoimmune diseases, we suggest that molecular mimicry could trigger both diseases, and thus explain their co-occurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.