Evidence map›Paper›PMID 28701883›Full record

ArticleJournal of ginseng research2017

20

Sang Mi Park, Eun Hye Jung, Jae Kwang Kim, Kyung Hwan Jegal, Chung A Park, Il Je Cho, Sang Chan Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Antioxidants (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sang Mi ParkMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Eun Hye JungMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Jae Kwang KimMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Kyung Hwan JegalMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Chung A ParkCollege of Korean Medicine, Daegu Haany University, Daegu, Republic of Korea.
Il Je ChoMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Sang Chan KimMRC-GHF, Department of Herbal Formulation, College of Korean Medicine, Daegu Haany University, Gyeongsan, Republic of Korea.
Daegu Haany University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreviously, we reported that Korean Red Ginseng inhibited liver fibrosis in mice and reduced the expressions of fibrogenic genes in hepatic stellate cells (HSCs). The present study was undertaken to identify the major ginsenoside responsible for reducing the numbers of HSCs and the underlying mechanism involved.

methodsUsing LX-2 cells (a human immortalized HSC line) and primary activated HSCs, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide) assays were conducted to examine the cytotoxic effects of ginsenosides. H RESULTS AND

conclusionOf the 11 ginsenosides tested, 20

Indexed as

20S-protopanaxadiol (PPD)AMP-activated protein kinase (AMPK)apoptosishepatic stellate cells (HSCs)liver kinase B1 (LKB1)

Identifiers

PMID28701883
PMCPMC5489770
OpenAlexW2582539003

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.