ArticleJournal of the American Society of Nephrology : JASN2017
Blocking TGF-
Abstract read
In one paragraph
Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 55 citations in OpenAlex.
- An early prediction model for chronic kidney disease.Scientific reports · 2022Trial
- Proximal TGF-β Signaling in Chronic Injury: from a notorious fibrotic factor to a repair ally.Pflugers Archiv : European journal of physiology · 2026Review
- Inflammation in cardiovascular-kidney-metabolic syndrome: key roles and underlying mechanisms-a comprehensive review.Molecular and cellular biochemistry · 2025Review
- CCN5 negatively regulates TGF-β-induced endometriosis associated fibrosis through Wnt/β-catenin signaling via Smad3-dependent mechanism.Journal of translational medicine · 2025Article
- Modulation of TGF-β signaling new approaches toward kidney disease and fibrosis therapy.International journal of biological sciences · 2025Review
- The Dual Role and Therapeutic Implications of the Wnt/β-Catenin Pathway in Diabetic Kidney Disease.International journal of general medicine · 2025Review
- Dynamics of Wnt/β-catenin reporter activity throughout whole life in a naturally short-lived vertebrate.npj aging · 2024Article
- Intrinsic TGF-β signaling attenuates proximal tubule mitochondrial injury and inflammation in chronic kidney disease.Nature communications · 2023Article
- Inhibition of Transforming Growth Factor-β Improves Primary Renal Tubule Cell Differentiation in Long-Term Culture.Tissue engineering. Part A · 2023Article
- Assessment of the Relationship Between Inflammation and Glomerular Filtration Rate.Canadian journal of kidney health and disease · 2023Article
- Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation.The Journal of clinical investigation · 2022Article
- Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.JCI insight · 2022Article
- Kidney Injuries and Evolution of Chronic Kidney Diseases Due to Neonatal Hyperoxia Exposure Based on Animal Studies.International journal of molecular sciences · 2022Review
- Blocking cell cycle progression through CDK4/6 protects against chronic kidney disease.JCI insight · 2022Article
- Article
- The role of mineralocorticoid receptor activation in kidney inflammation and fibrosis.Kidney international supplements · 2022Review
- Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration.Cell reports · 2022Article
- Mechanosensitive miR-100 coordinates TGFβ and Wnt signaling in osteocytes during fluid shear stress.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Proximal tubule LPA1 and LPA2 receptors use divergent signaling pathways to additively increase profibrotic cytokine secretion.American journal of physiology. Renal physiology · 2021Article
- WNT-β-catenin signalling - a versatile player in kidney injury and repair.Nature reviews. Nephrology · 2021Review
Corrections and comments
- Commented on by
Authors and funding
13 authors at 5 institutions in 3 countries.
Stellor Nlandu-KhodoDivision of Nephrology, Department of Medicine and.
Surekha NeelisettyDivision of Nephrology, Department of Medicine and.
Melanie PhillipsDivision of Nephrology, Department of Medicine and.
Marika ManolopoulouDivision of Nephrology, Department of Medicine and.
Gautam BhaveDivision of Nephrology, Department of Medicine and.
Lauren MayAspirnaut Program.
Peter E ClarkUrologic Surgery.
Haichun YangPathology, Microbiology and Immunology.
Agnes B FogoDivision of Nephrology, Department of Medicine and.
Raymond C HarrisDivision of Nephrology, Department of Medicine and.
M Mark TaketoDivision of Experimental Therapeutics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ethan LeeDepartments of Cell and Developmental Biology.
Leslie S GewinDivision of Nephrology, Department of Medicine and l.gewin@vanderbilt.edu.
Bipar · FRKyoto University · JPPediatrics and Genetics · USVanderbilt University Medical Center · USVA Tennessee Valley Healthcare System · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MVANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6MVANTAGE:Consolidation to create the Vanderbilt Technologies for Advanced GenomicsG20RR030956 · NCRR · VANDERBILT UNIVERSITY · PI PIETENPOL, JENNIFER A · 2010 to 2010
$8.7MMechanism of Wnt signal transductionR35GM122516 · NIGMS · VANDERBILT UNIVERSITY · PI ETHAN LEE · 2017 to 2026
$5.8MRESOLUTION OF GLOMERULOSCLEROSISR01DK056942 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FOGO, AGNES B. · 2001 to 2021
$4.9MTGF-beta Pathways that Protect Epithelia in Chronic Renal InjuryR01DK108968 · NIDDK · WASHINGTON UNIVERSITY · PI GEWIN, LESLIE S · 2016 to 2025
$3.7MUndergraduate Research Internships in Pathobiology of Diabetic NephropathyR25DK096999 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BILLY GERALD HUDSON · 2012 to 2026
$1.6MRole of Peroxidasin in Glomerular Matrix HomeostasisK08DK097306 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BHAVE, GAUTAM · 2013 to 2017
$739kBLRD VA I01 BX003425NCI NIH HHS P30 CA068485NCRR NIH HHS G20 RR030956NCRR NIH HHS UL1 RR024975NEI NIH HHS P30 EY008126NIDDK NIH HHS K08 DK097306NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK056942NIDDK NIH HHS R01 DK108968NIDDK NIH HHS R25 DK096999NIGMS NIH HHS R35 GM122516Wellcome Trust
Abstract
The TGF-
Indexed as
AnimalsAristolochic Acidsbeta CateninCell NucleusCollagenCrosses, GeneticEpitheliumFemaleGene DeletionKidney Failure, ChronicKidney Tubules, ProximalMaleMiceMice, Inbred BALB CMice, KnockoutMice, Transgenicaristolochic acid IAristolochic Acidsbeta CateninCollagenCTNNB1 protein, mouseProtein Serine-Threonine KinasesReceptors, Transforming Growth Factor betaReceptor, Transforming Growth Factor-beta Type IITgfb1 protein, mouseTransforming Growth Factor beta1Wnt Proteinschronic kidney diseasefibrosisproximal tubulerenal epithelial cell
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.