Evidence map›Paper›PMID 28701506›Full record

ArticleJournal of the Royal Society, Interface2017

Modelling the host-pathogen interactions of macrophages and

Sybille Dühring, Jan Ewald, Sebastian Germerodt, Christoph Kaleta, Thomas Dandekar, Stefan Schuster

Open access · hybridAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Trends in mathematical modeling of host-pathogen interactions.Cellular and molecular life sciences : CMLS · 2020
    Review
  9. Review
  10. Article
  11. Identification of Antifungal Targets Based on Computer Modeling.Journal of fungi (Basel, Switzerland) · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sybille DühringDepartment of Bioinformatics, Friedrich-Schiller-University Jena, Jena, Germany sybille.duehring@uni-jena.de.ORCID 0000-0003-0837-5467
Jan EwaldDepartment of Bioinformatics, Friedrich-Schiller-University Jena, Jena, Germany.ORCID 0000-0002-9415-2317
Sebastian GermerodtDepartment of Bioinformatics, Friedrich-Schiller-University Jena, Jena, Germany.
Christoph KaletaResearch Group Medical Systems Biology, Institute for Experimental Medicine, Christian-Albrechts-University Kiel, Kiel, Germany.
Thomas DandekarBiocenter, Department of Bioinformatics, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Stefan SchusterDepartment of Bioinformatics, Friedrich-Schiller-University Jena, Jena, Germany.
Friedrich Schiller University Jena · DEChristian-Albrechts-Universität zu Kiel · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The release of fungal cells following macrophage phagocytosis, called non-lytic expulsion, is reported for several fungal pathogens. On one hand, non-lytic expulsion may benefit the fungus in escaping the microbicidal environment of the phagosome. On the other hand, the macrophage could profit in terms of avoiding its own lysis and being able to undergo proliferation. To analyse the causes of non-lytic expulsion and the relevance of macrophage proliferation in the macrophage-

Indexed as

Game TheoryModels, BiologicalBiological EvolutionCandida albicansComputer SimulationHumansMacrophagesCandida albicansdynamic optimizationgame theorymacrophage replicationnon-lytic expulsionpathogenic fungi

Identifiers

PMID28701506
PMCPMC5550964
OpenAlexW2735822339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.