Evidence map›Paper›PMID 28701486›Full record

ReviewCancer research2017

Long Noncoding RNA and Cancer: A New Paradigm.

Arunoday Bhan, Milad Soleimani, Subhrangsu S Mandal

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,764 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,764citing papers in PubMed, 2 pooled it
74.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,764 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3,111 citations in OpenAlex.

  1. Pooled it
  2. Role of SNHGs in Adverse Prognostic Factors in Cervical Cancer: A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2025
    Pooled it
  3. Cell plasticity in cancer and therapy resistance.Experimental & molecular medicine · 2026
    Review
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1,704 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arunoday BhanGene Regulation and Epigenetics Research Lab, Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas.
Milad SoleimaniGene Regulation and Epigenetics Research Lab, Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas.
Subhrangsu S MandalGene Regulation and Epigenetics Research Lab, Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas. smandal@uta.edu.
The University of Texas at Arlington · US

Funding

Endocrine Disruptors: Assessment of endocrine disruption activity, mechanism andR15ES019129 · NIEHS · UNIVERSITY OF TEXAS ARLINGTON · PI MANDAL, SUBHRANGSU S · 2010 to 2010
$445k
NIEHS NIH HHS R15 ES019129
6 · The paper itself

Abstract

In addition to mutations or aberrant expression in the protein-coding genes, mutations and misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to play major roles in cancer. Genome-wide association studies of tumor samples have identified a large number of lncRNAs associated with various types of cancer. Alterations in lncRNA expression and their mutations promote tumorigenesis and metastasis. LncRNAs may exhibit tumor-suppressive and -promoting (oncogenic) functions. Because of their genome-wide expression patterns in a variety of tissues and their tissue-specific expression characteristics, lncRNAs hold strong promise as novel biomarkers and therapeutic targets for cancer. In this article, we have reviewed the emerging functions and association of lncRNAs in different types of cancer and discussed their potential implications in cancer diagnosis and therapy.

Indexed as

HumansNeoplasmsRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID28701486
PMCPMC8330958
OpenAlexW2735687500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.