Evidence map›Paper›PMID 28701485›Full record

ArticleThe EMBO journal2017

GT-rich promoters can drive RNA pol II transcription and deposition of H2A.Z in African trypanosomes.

Carolin Wedel, Konrad U Förstner, Ramona Derr, T Nicolai Siegel

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 89 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carolin WedelResearch Center for Infectious Diseases, Universität Würzburg, Würzburg, Germany.ORCID 0000-0001-6730-2220
Konrad U FörstnerCore Unit Systems Medicine, Universität Würzburg, Würzburg, Germany.ORCID 0000-0002-1481-2996
Ramona DerrResearch Center for Infectious Diseases, Universität Würzburg, Würzburg, Germany.
T Nicolai SiegelResearch Center for Infectious Diseases, Universität Würzburg, Würzburg, Germany n.siegel@lmu.de.ORCID 0000-0002-1715-7907
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide transcription studies are revealing an increasing number of "dispersed promoters" that, unlike "focused promoters", lack well-conserved sequence motifs and tight regulation. Dispersed promoters are nevertheless marked by well-defined chromatin structures, suggesting that specific sequence elements must exist in these unregulated promoters. Here, we have analyzed regions of transcription initiation in the eukaryotic parasite

Indexed as

Promoter Regions, GeneticHistonesRNA Polymerase IITranscription, GeneticTrypanosoma brucei bruceiHistonesRNA Polymerase IIcore promoterhistone variantnucleosome occupancyTrypanosoma brucei

Identifiers

PMID28701485
PMCPMC5579346
OpenAlexW2734628066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.