Evidence map›Paper›PMID 28701467›Full record

ReviewClinical and vaccine immunology : CVI2017

The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.

Michael J Brennan, Rachel Tanner, Sheldon Morris, Thomas J Scriba, Jacqueline M Achkar, Andrea Zelmer, David A Hokey, Angelo Izzo, Sally Sharpe, Ann Williams and 6 more

Open access · diamondAbstract readReview
In one paragraph

Review in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  11. Control ofFrontiers in immunology · 2023
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  15. TheF1000Research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Michael J BrennanAeras, Rockville, Maryland, USA.
Rachel TannerThe Jenner Institute, University of Oxford, Oxford, United Kingdom rachel.tanner@ndm.ox.ac.uk.
Sheldon MorrisCenter for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA.
Thomas J ScribaSouth African Tuberculosis Vaccine Initiative and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
Jacqueline M AchkarDepartments of Medicine, Microbiology, and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.
Andrea ZelmerDepartment of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom.
David A HokeyAeras, Rockville, Maryland, USA.
Angelo IzzoColorado State University, Fort Collins, Colorado, USA.
Sally SharpePublic Health England, Porton Down, Salisbury, United Kingdom.
Ann WilliamsPublic Health England, Porton Down, Salisbury, United Kingdom.
Adam Penn-NicholsonSouth African Tuberculosis Vaccine Initiative and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
Mzwandile ErasmusSouth African Tuberculosis Vaccine Initiative and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
Elena StylianouThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Daniel F HoftSaint Louis University, St. Louis, Missouri, USA.
Helen McShaneThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Helen A FletcherDepartment of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID http://orcid.org/0000-0002-0435-1006
University of Cape Town · ZAUniversity of Oxford · GBAeras · USLondon School of Hygiene & Tropical Medicine · GBPublic Health England · GBAlbert Einstein College of Medicine · USCenter for Biologics Evaluation and Research · USColorado State University · USSaint Louis University · US

Funding

Discovery of Biological and Immunological Biomarkers for TB VaccinesU18FD004012 · FDA · AERAS · PI BRENNAN, MICHAEL · 2010 to 2012
$853k
FDA HHS U18 FD004012Wellcome Trust
6 · The paper itself

Abstract

The development of a functional biomarker assay in the tuberculosis (TB) field would be widely recognized as a major advance in efforts to develop and to test novel TB vaccine candidates efficiently. We present preliminary studies using mycobacterial growth inhibition assays (MGIAs) to detect

Indexed as

AnimalsBCG VaccineColony Count, MicrobialHumansInfantIntersectoral CollaborationMycobacterium tuberculosisReproducibility of ResultsSouth AfricaSpecies SpecificityTuberculosisTuberculosis VaccinesBCG VaccineTuberculosis Vaccinescorrelates of immunityMGIAmycobacterial growth inhibition assaytuberculosisvaccines

Identifiers

PMID28701467
PMCPMC5585695
OpenAlexW2735330439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.